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Literature summary extracted from

  • Mank, N.; Arnette, A.; Klapper, V.; Offermann, L.; Chruszcz, M.
    Structure of dihydrodipicolinate synthase from the commensal bacterium Bacteroides thetaiotaomicron at 2.1 A resolution (2015), Acta Crystallogr. Sect. F, 71, 449-454 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.3.3.7 expression in Escherichia coli Bacteroides thetaiotaomicron

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
4.3.3.7 sitting-drop vapor-diffusion method at room temperature Bacteroides thetaiotaomicron

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.3.3.7 pyruvate + L-aspartate-4-semialdehyde Bacteroides thetaiotaomicron the enzyme catalyzes a step of the diaminopimelate biosynthetic pathway of lysine (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O
-
?
4.3.3.7 pyruvate + L-aspartate-4-semialdehyde Bacteroides thetaiotaomicron ATCC 29148 the enzyme catalyzes a step of the diaminopimelate biosynthetic pathway of lysine (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O
-
?

Organism

EC Number Organism UniProt Comment Textmining
4.3.3.7 Bacteroides thetaiotaomicron Q8A3Z0
-
-
4.3.3.7 Bacteroides thetaiotaomicron ATCC 29148 Q8A3Z0
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.3.3.7 pyruvate + L-aspartate-4-semialdehyde
-
Bacteroides thetaiotaomicron (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O
-
?
4.3.3.7 pyruvate + L-aspartate-4-semialdehyde the enzyme catalyzes a step of the diaminopimelate biosynthetic pathway of lysine Bacteroides thetaiotaomicron (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O
-
?
4.3.3.7 pyruvate + L-aspartate-4-semialdehyde
-
Bacteroides thetaiotaomicron ATCC 29148 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O
-
?
4.3.3.7 pyruvate + L-aspartate-4-semialdehyde the enzyme catalyzes a step of the diaminopimelate biosynthetic pathway of lysine Bacteroides thetaiotaomicron ATCC 29148 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O
-
?

Synonyms

EC Number Synonyms Comment Organism
4.3.3.7 DapA
-
Bacteroides thetaiotaomicron

General Information

EC Number General Information Comment Organism
4.3.3.7 metabolism the enzyme catalyzes a step of the diaminopimelate biosynthetic pathway of lysine Bacteroides thetaiotaomicron