Literature summary extracted from

Perduca, M.; Bovi, M.; Bertinelli, M.; Bertini, E.; Destefanis, L.; Carrizo, M.E.; Capaldi, S.; Monaco, H.L.
High-resolution structures of mutants of residues that affect access to the ligand-binding cavity of human lipocalin-type prostaglandin D synthase (2014), Acta Crystallogr. Sect. D, 70, 2125-2138 .

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
5.3.99.2	expressed in Escherichia coli BL21(DE3) cells	Homo sapiens

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
5.3.99.2	mutant enzymes C65A/K59A, C65A, C65A/W54F, C65A/W112F and C65A/W54F/W112F hanging drop vapor diffusion method, using 0.2 M ammonium sulfate, 30% (w/v) PEG 4000	Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
5.3.99.2	Prostaglandin H2	Homo sapiens	-	Prostaglandin D2	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
5.3.99.2	Homo sapiens	P41222	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
5.3.99.2	chitin column chromatography and Superdex G-75 gel filtration	Homo sapiens

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5.3.99.2	Prostaglandin H2	-	Homo sapiens	Prostaglandin D2	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
5.3.99.2	L-PGDS	-	Homo sapiens
5.3.99.2	lipocalin-type prostaglandin d synthase	-	Homo sapiens
5.3.99.2	Prostaglandin-H2 D-isomerase	-	Homo sapiens

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Release 2023.1 (January 2023)