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Literature summary extracted from

  • Xu, X.; Wang, C.; Chen, J.; Yang, S.
    Streptomyces virginiae PPDC is a new type of phenylpyruvate decarboxylase composed of two subunits (2017), ACS Chem. Biol., 12, 2008-2014 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.1.43 expression in Escherichia coli Streptomyces virginiae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.43 1.13
-
 phenylpyruvate allosteric enzyme, Hill coefficient 4.7, pH 7.5, temperature not specified in the publication Streptomyces virginiae

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.1.1.43 Mg2+ required Streptomyces virginiae

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.43 Streptomyces virginiae A0A222AKA3 alpha subunit
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.43 Phenylpyruvate
-
 Streptomyces virginiae Phenylacetaldehyde + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.43 ? x * 41000, alpha-subunit, plus x * 38000, beta-subunit, SDS-PAGE Streptomyces virginiae

Synonyms

EC Number Synonyms Comment Organism
4.1.1.43 PPDC
-
 Streptomyces virginiae

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.1.1.43 0.0055
-
 phenylpyruvate allosteric enzyme, Hill coefficient 4.7, pH 7.5, temperature not specified in the publication Streptomyces virginiae

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.43 thiamine diphosphate
-
 Streptomyces virginiae

kcat/KM [mM/s]

EC Number kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
4.1.1.43 0.0058
-
 phenylpyruvate allosteric enzyme, Hill coefficient 4.7, pH 7.5, temperature not specified in the publication Streptomyces virginiae