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Literature summary extracted from

  • Uehara, S.; Murayama, N.; Nakanishi, Y.; Nakamura, C.; Hashizume, T.; Zeldin, D.C.; Yamazaki, H.; Uno, Y.
    Immunochemical quantification of cynomolgus CYP2J2, CYP4A and CYP4F enzymes in liver and small intestine (2015), Xenobiotica, 45, 124-130 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.B9 Macaca fascicularis A8CBR8 isoform Cyp4F11
-
1.14.14.B9 Macaca fascicularis A8CBS0 isoform Cyp4F12
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.B9 liver isoforms CYP4F2/3, CYP4F11 and CYP4F12, vary 1.3- to 4.3fold, representing 8.0, 2.7 and 0.3% of total immunoquantified CYP1-4 proteins Macaca fascicularis
-
1.14.14.B9 small intestine isoforms CYP4F2/3, CYP4F11 and CYP4F12 vary 2.4- to 9.7fold, representing 36.4, 2.4 and 9.3% of total immunoquantified CYP1-4 proteins, respectively. CYP4F is the most abundant P450 subfamily in small intestines Macaca fascicularis
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.B9 astemizole + [reduced NADPH-hemoprotein reductase] + O2
-
 Macaca fascicularis ? + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.B9 CYP4F11
-
 Macaca fascicularis
1.14.14.B9 CYP4F12
-
 Macaca fascicularis