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Literature summary extracted from

  • Yildirim, K.; Kuru, A.; Keskin, E.; Salihoglu, A.; Bukum, N.
    Biotransformation of androst-4-ene-3,17-dione by some fungi (2017), J. Chem. Res., 41, 594-597 .
No PubMed abstract available

Organism

EC Number Organism UniProt Comment Textmining
1.14.99.12 Aspergillus candidus
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1.14.99.12 Aspergillus candidus MRC 200634
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1.14.99.12 Aspergillus tamarii
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1.14.99.12 Aspergillus tamarii MRC 72400
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1.14.99.12 Aspergillus wentii
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1.14.99.12 Aspergillus wentii MRC 200316
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1.14.99.12 Mucor hiemalis
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1.14.99.12 Mucor hiemalis MRC 70325
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.99.12 androst-4-ene-3,17-dione + AH2 + O2
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 Mucor hiemalis 14alpha-hydroxyandrost-4-ene-3,17-dione + 14alpha,17beta-dihydroxyandrost-4-en-3-one + 7alpha,17beta-dihydroxyandrost-4-en-3-one + A + H2O
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 ?
1.14.99.12 androst-4-ene-3,17-dione + AH2 + O2
-
 Mucor hiemalis MRC 70325 14alpha-hydroxyandrost-4-ene-3,17-dione + 14alpha,17beta-dihydroxyandrost-4-en-3-one + 7alpha,17beta-dihydroxyandrost-4-en-3-one + A + H2O
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 ?
1.14.99.12 androst-4-ene-3,17-dione + AH2 + O2
-
 Aspergillus wentii 14alpha-hydroxyandrost-4-ene-3,17-dione + 6beta-hydroxyandrost-4-ene-3,17-dione + A + H2O
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 ?
1.14.99.12 androst-4-ene-3,17-dione + AH2 + O2
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 Aspergillus wentii MRC 200316 14alpha-hydroxyandrost-4-ene-3,17-dione + 6beta-hydroxyandrost-4-ene-3,17-dione + A + H2O
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 ?
1.14.99.12 androst-4-ene-3,17-dione + AH2 + O2
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 Aspergillus tamarii 17beta-hydroxyandrost-4-en-3-one + 11beta-hydroxyandrost-4-ene-3,17-dione + 17alpha-oxa-D-homo-androst-4-ene-3,17-dione + A + H2O
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 ?
1.14.99.12 androst-4-ene-3,17-dione + AH2 + O2
-
 Aspergillus tamarii MRC 72400 17beta-hydroxyandrost-4-en-3-one + 11beta-hydroxyandrost-4-ene-3,17-dione + 17alpha-oxa-D-homo-androst-4-ene-3,17-dione + A + H2O
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 ?
1.14.99.12 androst-4-ene-3,17-dione + AH2 + O2
-
 Aspergillus candidus 17beta-hydroxyandrost-4-en-3-one + 14alpha-hydroxyandrost-4-ene-3,17-dione + 11alpha-hydroxyandrost-4-ene-3,17-dione + 15beta,17beta-dihydroxyandrost-4-en-3-one + 11alpha,17beta-dihydroxyandrost-4-en-3-one + 15alpha,17beta-dihydroxyandrost-4-en-3-one + A + H2O
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 ?
1.14.99.12 androst-4-ene-3,17-dione + AH2 + O2
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 Aspergillus candidus MRC 200634 17beta-hydroxyandrost-4-en-3-one + 14alpha-hydroxyandrost-4-ene-3,17-dione + 11alpha-hydroxyandrost-4-ene-3,17-dione + 15beta,17beta-dihydroxyandrost-4-en-3-one + 11alpha,17beta-dihydroxyandrost-4-en-3-one + 15alpha,17beta-dihydroxyandrost-4-en-3-one + A + H2O
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 ?