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Literature summary extracted from

  • Rokob, T.
    Pathways for arene oxidation in non-heme diiron enzymes lessons from computational studies on benzoyl coenzyme A epoxidase (2016), J. Am. Chem. Soc., 138, 14623-14638 .
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.14.13.208 Fe2+ a non-heme diiron enzyme Aromatoleum evansii

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.13.208 benzoyl-CoA + NADPH + H+ + O2 Aromatoleum evansii
-
 2,3-epoxy-2,3-dihydrobenzoyl-CoA + NADP+ + H2O
-
 ?
1.14.13.208 benzoyl-CoA + NADPH + H+ + O2 Aromatoleum evansii KB 740
-
 2,3-epoxy-2,3-dihydrobenzoyl-CoA + NADP+ + H2O
-
 ?
1.14.13.208 additional information Aromatoleum evansii benzoyl-CoA epoxidase is a dinuclear iron enzyme that catalyzes the epoxidation reaction of the aromatic ring of benzoyl-CoA with chemo-, regio- and stereo-selectivity ?
-
 ?
1.14.13.208 additional information Aromatoleum evansii KB 740 benzoyl-CoA epoxidase is a dinuclear iron enzyme that catalyzes the epoxidation reaction of the aromatic ring of benzoyl-CoA with chemo-, regio- and stereo-selectivity ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.208 Aromatoleum evansii
-
-
-
1.14.13.208 Aromatoleum evansii KB 740
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.14.13.208 benzoyl-CoA + NADPH + H+ + O2 = 2,3-epoxy-2,3-dihydrobenzoyl-CoA + NADP+ + H2O molecular reaction mechanism analysis, different pathways are possible, detailed overview Aromatoleum evansii
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.208 benzoyl-CoA + NADPH + H+ + O2
-
 Aromatoleum evansii 2,3-epoxy-2,3-dihydrobenzoyl-CoA + NADP+ + H2O
-
 ?
1.14.13.208 benzoyl-CoA + NADPH + H+ + O2
-
 Aromatoleum evansii KB 740 2,3-epoxy-2,3-dihydrobenzoyl-CoA + NADP+ + H2O
-
 ?
1.14.13.208 additional information benzoyl-CoA epoxidase is a dinuclear iron enzyme that catalyzes the epoxidation reaction of the aromatic ring of benzoyl-CoA with chemo-, regio- and stereo-selectivity Aromatoleum evansii ?
-
 ?
1.14.13.208 additional information benzoyl-CoA epoxidase is a dinuclear iron enzyme that catalyzes the epoxidation reaction of the aromatic ring of benzoyl-CoA with chemo-, regio- and stereo-selectivity Aromatoleum evansii KB 740 ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.13.208 benzoyl coenzyme A epoxidase
-
 Aromatoleum evansii
1.14.13.208 benzoyl-CoA epoxidase
-
 Aromatoleum evansii
1.14.13.208 BoxB
-
 Aromatoleum evansii

General Information

EC Number General Information Comment Organism
1.14.13.208 additional information usage of PDB ID 3PM5 for enzyme structure modeling and simulation, quantum mechanics/molecular mechanics calculations, overview. Four general pathways for oxidizing aromatic rings are determined Aromatoleum evansii