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Literature summary extracted from

  • Aggarwal, N.; Goswami, S.V.; Khandelwal, P.; Sehgal, N.
    Aromatase activity in brain and ovary seasonal variations correlated with circannual gonadal cycle in the catfish, Heteropneustes fossilis (2014), Indian J. Exp. Biol., 52, 527-537 .
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.14 Heteropneustes fossilis
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.14 hypothalamus in the female, activity is detecable throughout the year Heteropneustes fossilis
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1.14.14.14 ovary activity is found only during vitellogenesis. At the completion of vitellogenesis, ovarian aromatase activity declines sharply resulting in elevation of plasma testosterone levels Heteropneustes fossilis
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.14 androst-4-ene-3,17-dione + 3 O2 + 3 reduced flavoproteins
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 Heteropneustes fossilis estrone + formate + 4 H2O + 3 oxidized flavoproteins
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 ?
1.14.14.14 testosterone + 3 O2 + 3 reduced flavoproteins
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 Heteropneustes fossilis 17beta-estradiol + formate + 4 H2O + 3 oxidized flavoproteins
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 ?

Expression

EC Number Organism Comment Expression
1.14.14.14 Heteropneustes fossilis hypothalamic aromatase levels increase two times during annual gonadal cycle, once in a fully gravid fish and then in a reproductively quiescent fish additional information