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Literature summary extracted from

  • Wang, H.; Pan, Y.; Hu, P.; Zhu, Y.; Li, J.; Jiang, X.; Liu, G.
    The autophagy-related gene Acatg1 is involved in conidiation and cephalosporin production in Acremonium chrysogenum (2014), Fungal Genet. Biol., 69, 65-74 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.21.3.1 expressed in Escherichia coli BL21(DE3) cells Acremonium chrysogenum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.21.3.1 N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O2 Acremonium chrysogenum
-
 isopenicillin N + H2O
-
 ?
1.21.3.1 N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O2 Acremonium chrysogenum 3.3795
-
 isopenicillin N + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.21.3.1 Acremonium chrysogenum
-
-
-
1.21.3.1 Acremonium chrysogenum 3.3795
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.21.3.1 Ni-NTA agarose column chromatography Acremonium chrysogenum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.21.3.1 N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O2
-
 Acremonium chrysogenum isopenicillin N + H2O
-
 ?
1.21.3.1 N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O2
-
 Acremonium chrysogenum 3.3795 isopenicillin N + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.21.3.1 IPNS
-
 Acremonium chrysogenum
1.21.3.1 isopenicillin N synthase
-
 Acremonium chrysogenum
1.21.3.1 PcbC
-
 Acremonium chrysogenum

Expression

EC Number Organism Comment Expression
1.21.3.1 Acremonium chrysogenum the quantity of the enzyme in wild type decreases drastically from 5 days fermentation when autophagy is induced down

General Information

EC Number General Information Comment Organism
1.21.3.1 metabolism the enzyme is involved in cephalosporin biosynthesis Acremonium chrysogenum