EC Number | Application | Comment | Organism |
---|---|---|---|
1.14.11.11 | synthesis | overexpression of the enzyme (H6H) enhances the biosynthesis of anisodamine and scopolamine in hairy root cultures of Scopolia lurida, which should improve its commercial value. The tropane alkaloids anisodamine and and scopolamine are clinically used as anticholinergic agents | Hyoscyamus niger |
EC Number | Cloned (Comment) | Organism |
---|---|---|
1.14.11.11 | overexpression in hairy root cultures of Scopolia lurida | Hyoscyamus niger |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.11.11 | Hyoscyamus niger | P24397 | - |
- |
1.14.20.13 | Anisodus luridus | - |
- |
- |
1.14.20.13 | Hyoscyamus niger | P24397 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.20.13 | root | - |
Hyoscyamus niger | - |
1.14.20.13 | root | - |
Anisodus luridus | - |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.11.11 | H6H | - |
Hyoscyamus niger |
1.14.11.11 | hyoscyamine 6beta-hydroxylase | - |
Hyoscyamus niger |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.14.20.13 | physiological function | root cultures overexpressing the enzyme show remarkably elevated levels of scopolamine and anisodamine. Hyoscyamine 6beta-hydroxylases from both Scopolia lurida and Hyoscyamus niger promote anisodamine production at similar levels in Scopolia lurida root cultures. Hyoscyamus niger hyoscyamine 6beta-hydroxylase overexpressing root cultures have more scopolamine in them than Scopolia lurida hyoscyamine 6beta-hydroxylase-overexpressing root cultures | Hyoscyamus niger |
1.14.20.13 | physiological function | root cultures overexpressing the enzyme show remarkably elevated levels of scopolamine and anisodamine. Hyoscyamine 6beta-hydroxylases from both Scopolia lurida and Hyoscyamus niger promote anisodamine production at similar levels in Scopolia lurida root cultures. Hyoscyamus niger hyoscyamine 6beta-hydroxylase overexpressing root cultures have more scopolamine in them than Scopolia lurida hyoscyamine 6beta-hydroxylase-overexpressing root cultures | Anisodus luridus |