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Literature summary extracted from

  • Nakazawa, H.
    Inhibition of aromatic L-amino acid decarboxylase from Micrococcus percitreus by substrate analogs (1987), Agric. Biol. Chem., 51, 2531-2537 .
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.28 2-Phenylethylamine competitive inhibition, 80% inhibition at 0.5 mM Micrococcus percitreus
4.1.1.28 3-Indoleacetamide 27% inhibition at 0.25 mM Micrococcus percitreus
4.1.1.28 3-Indolealdehyde 33% inhibition at 0.25 mM Micrococcus percitreus
4.1.1.28 alpha-methyl-DL-phenylalanine competitive inhibition Micrococcus percitreus
4.1.1.28 DL-m-tyrosine 50% inhibition at 4 mM Micrococcus percitreus
4.1.1.28 dopamine complete inhibition at 0.5 mM Micrococcus percitreus
4.1.1.28 epinephrine 30% inhibition at 4 mM Micrococcus percitreus
4.1.1.28 histamine 1% inhibition at 4 mM Micrococcus percitreus
4.1.1.28 L-Dopa competitive inhibition, 98% inhibition at 1 mM Micrococcus percitreus
4.1.1.28 L-histidine 5% inhibition at 4 mM Micrococcus percitreus
4.1.1.28 L-phenylalanine uncompetitive inhibition, 53% inhibition at 0.5 mM Micrococcus percitreus
4.1.1.28 L-tyrosine uncompetitive inhibition, 38% inhibition at 0.5 mM Micrococcus percitreus
4.1.1.28 additional information not inhibited by D-tryptophan, kynuramine, octopamine, and 3-indoleacetate Micrococcus percitreus
4.1.1.28 norepinephrine 40% inhibition at 4 mM Micrococcus percitreus
4.1.1.28 potassium bicarbonate 57% inhibition at 1 M Micrococcus percitreus
4.1.1.28 serotonin 2% inhibition at 4 mM Micrococcus percitreus
4.1.1.28 tryptamine 5% inhibition at 1 mM Micrococcus percitreus
4.1.1.28 tyramine competitive inhibition, 71% inhibition at 0.5 mM Micrococcus percitreus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.28 L-tryptophan Micrococcus percitreus
-
 tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan Micrococcus percitreus AJ 1065
-
 tryptamine + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.28 Micrococcus percitreus
-
-
-
4.1.1.28 Micrococcus percitreus AJ 1065
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.28 L-tryptophan
-
 Micrococcus percitreus tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan
-
 Micrococcus percitreus AJ 1065 tryptamine + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.28 Aromatic L-amino acid decarboxylase
-
 Micrococcus percitreus