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Literature summary extracted from

  • Gao, W.; Wu, Z.; Sun, J.; Ni, X.; Xia, H.
    Modulation of kanamycin B and kanamycin A biosynthesis in Streptomyces kanamyceticus via metabolic engineering (2017), PLoS ONE, 12, e0181971 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.11.37 expressed in Escherichia coli DH5alpha cells Streptomyces kanamyceticus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.14.11.37 Fe2+ required Streptomyces kanamyceticus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.11.37 kanamycin B + 2-oxoglutarate + O2 Streptomyces kanamyceticus
-
 2'-dehydrokanamycin A + succinate + NH3 + CO2
-
 ?
1.14.11.37 kanamycin B + 2-oxoglutarate + O2 Streptomyces kanamyceticus CG305
-
 2'-dehydrokanamycin A + succinate + NH3 + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.11.37 Streptomyces kanamyceticus Q6L732
-
-
1.14.11.37 Streptomyces kanamyceticus CG305 Q6L732
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.11.37 kanamycin B + 2-oxoglutarate + O2
-
 Streptomyces kanamyceticus 2'-dehydrokanamycin A + succinate + NH3 + CO2
-
 ?
1.14.11.37 kanamycin B + 2-oxoglutarate + O2
-
 Streptomyces kanamyceticus CG305 2'-dehydrokanamycin A + succinate + NH3 + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.11.37 kanJ
-
 Streptomyces kanamyceticus