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Literature summary extracted from
- Two novel flavin-containing monooxygenases involved in biosynthesis of aliphatic glucosinolates (2016), Front. Plant Sci., 7, 1292 .
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.14.13.237 | expressed in Escherichia coli Top10 cells | Arabidopsis thaliana |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.13.8 | methylthioalkyl glucosinolate + NADPH + H+ + O2 | Arabidopsis thaliana | - |
methylsulfinylalkyl glucosinolate S-oxide + NADP+ + H2O | - |
? |  |
| 1.14.13.237 | an omega-(methylthio)alkyl-glucosinolate + NADPH + H+ + O2 | Arabidopsis thaliana | - |
an omega-(methylsulfinyl)alkyl-glucosinolate + NADP+ + H2O | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.13.8 | Arabidopsis thaliana | - |
- |
- |
| 1.14.13.237 | Arabidopsis thaliana | - |
ecotype Col-0 | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.13.8 | calyx | - |
Arabidopsis thaliana | - |
| 1.14.13.8 | carpel | - |
Arabidopsis thaliana | - |
| 1.14.13.8 | root | - |
Arabidopsis thaliana | - |
| 1.14.13.8 | stamen | - |
Arabidopsis thaliana | - |
| 1.14.13.8 | vascular tissue | - |
Arabidopsis thaliana | - |
| 1.14.13.237 | cotyledon | - |
Arabidopsis thaliana | - |
| 1.14.13.237 | hypocotyl | - |
Arabidopsis thaliana | - |
| 1.14.13.237 | leaf | - |
Arabidopsis thaliana | - |
| 1.14.13.237 | radicle | - |
Arabidopsis thaliana | - |
| 1.14.13.237 | root | - |
Arabidopsis thaliana | - |
| 1.14.13.237 | seedling | - |
Arabidopsis thaliana | - |
| 1.14.13.237 | vascular tissue | - |
Arabidopsis thaliana | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.13.8 | methylthioalkyl glucosinolate + NADPH + H+ + O2 | - |
Arabidopsis thaliana | methylsulfinylalkyl glucosinolate S-oxide + NADP+ + H2O | - |
? | |
| 1.14.13.237 | 3-methylthiopropyl-glucosinolate + NADPH + H+ + O2 | - |
Arabidopsis thaliana | 3-methylsulfinylpropyl-glucosinolate + NADP+ + H2O | - |
? | |
| 1.14.13.237 | 4-methylthiobutyl-glucosinolate + NADPH + H+ + O2 | - |
Arabidopsis thaliana | 4-methylsulfinylbutyl-glucosinolate + NADP+ + H2O | - |
? | |
| 1.14.13.237 | 5-methylthiopentyl-glucosinolate + NADPH + H+ + O2 | - |
Arabidopsis thaliana | 5-methylsulfinylpentyl-glucosinolate + NADP+ + H2O | - |
? | |
| 1.14.13.237 | 6-methylthiohexyl-glucosinolate + NADPH + H+ + O2 | - |
Arabidopsis thaliana | 6-methylsulfinylhexyl-glucosinolate + NADP+ + H2O | - |
? | |
| 1.14.13.237 | 7-methylthioheptyl-glucosinolate + NADPH + H+ + O2 | - |
Arabidopsis thaliana | 7-methylsulfinylheptyl-glucosinolate + NADP+ + H2O | - |
? | |
| 1.14.13.237 | 8-methylthiooctyl-glucosinolate + NADPH + H+ + O2 | - |
Arabidopsis thaliana | 8-methylsulfinyloctyl-glucosinolate + NADP+ + H2O | - |
? | |
| 1.14.13.237 | an omega-(methylthio)alkyl-glucosinolate + NADPH + H+ + O2 | - |
Arabidopsis thaliana | an omega-(methylsulfinyl)alkyl-glucosinolate + NADP+ + H2O | - |
? | |
| 1.14.13.237 | desulfo-4-methylsulfinylbutyl-glucosinolate + NADPH + H+ + O2 | - |
Arabidopsis thaliana | desulfo-4-methylsulfinylbutyl-glucosinolate + NADP+ + H2O | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.13.8 | FMOGS-OX6 | - |
Arabidopsis thaliana |
| 1.14.13.8 | FMOGS-OX7 | - |
Arabidopsis thaliana |
| 1.14.13.237 | flavin-containing monooxygenase | - |
Arabidopsis thaliana |
| 1.14.13.237 | FMOGS-OX1 | isoform | Arabidopsis thaliana |
| 1.14.13.237 | FMOGS-OX2 | isoform | Arabidopsis thaliana |
| 1.14.13.237 | FMOGS-OX3 | isoform | Arabidopsis thaliana |
| 1.14.13.237 | FMOGS-OX4 | isoform | Arabidopsis thaliana |
| 1.14.13.237 | FMOGS-OX5 | isoform | Arabidopsis thaliana |
| 1.14.13.237 | FMOGS-OX6 | isoform | Arabidopsis thaliana |
| 1.14.13.237 | FMOGS-OX7 | isoform | Arabidopsis thaliana |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.13.8 | FAD | - |
Arabidopsis thaliana | |
| 1.14.13.8 | NADPH | - |
Arabidopsis thaliana | |
| 1.14.13.237 | flavin | - |
Arabidopsis thaliana | |
| 1.14.13.237 | NADPH | - |
Arabidopsis thaliana | |
Expression
| EC Number | Organism | Comment | Expression |
|---|---|---|---|
| 1.14.13.8 | Arabidopsis thaliana | the expression of both isoforms FMOGS-OX6 and FMOGS-OX7 is strongly induced by salicylic acid | up |
| 1.14.13.8 | Arabidopsis thaliana | the expression of both isoforms FMOGS-OX6 and FMOGS-OX7 is strongly inhibited by methyl jasmonate. Abscisic acid promotes the expression of isoform FMOGS-OX6 significantly but does not affect isoform FMOGS-OX7 considerably | up |
| 1.14.13.237 | Arabidopsis thaliana | isoforms FMOGS-OX1, FMOGS-OX2, FMOGS-OX6, and MYB28 show upregulation (5fold) toward absisic acid, isoforms FMOGS-OX5, FMOGS-OX6, and FMOGS-OX7 toward 20 mM 20 mM 1-aminocyclopropane-1-carboxylic acid, isoform FMOGS-OX1 toward 0.05 mM methyl jasmonate, isoform FMOGS-OX7 toward 0.2 mM salicylic acid, and isoforms FMOGS-OX2 and FMOGS-OX5 toward 0.1 mM iodoacetic acid | up |
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Release 2023.1 (January 2023)
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