Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Xie, D.; Lu, J.; Xie, J.; Cui, J.; Li, T.F.; Wang, Y.C.; Chen, Y.; Gong, N.; Li, X.Y.; Fu, L.; Wang, Y.X.
    Discovery and analgesic evaluation of 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione as a novel potent D-amino acid oxidase inhibitor (2016), Eur. J. Med. Chem., 117, 19-32 .
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.3 1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 2,3-dioxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine-7-carboxylic acid
-
 Homo sapiens
1.4.3.3 2,3-dioxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine-7-carboxylic acid
-
 Rattus norvegicus
1.4.3.3 2,3-dioxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine-7-carboxylic acid
-
 Sus scrofa
1.4.3.3 3-hydroxyquinolin-2-one
-
 Homo sapiens
1.4.3.3 3-hydroxyquinolin-2-one
-
 Rattus norvegicus
1.4.3.3 3-hydroxyquinolin-2-one
-
 Sus scrofa
1.4.3.3 6-(benzyloxy)-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 6-(benzyloxy)-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 6-(benzyloxy)-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 6-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 6-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 6-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 6-chlorobenzo[d]isoxazol-3-ol
-
 Homo sapiens
1.4.3.3 6-chlorobenzo[d]isoxazol-3-ol
-
 Rattus norvegicus
1.4.3.3 6-chlorobenzo[d]isoxazol-3-ol
-
 Sus scrofa
1.4.3.3 6-ethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 6-ethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 6-ethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione .
-
 Rattus norvegicus
1.4.3.3 6-methoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 6-methoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 6-methoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 6-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 6-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 6-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 6-phenethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 6-phenethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 6-phenethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 7,8-dibromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 7,8-dibromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 7,8-dibromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 7,8-dichloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 7,8-dichloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 7,8-dichloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 7-bromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 7-bromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 7-bromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 7-bromo-8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 7-bromo-8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 7-bromo-8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 7-bromo-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 7-bromo-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 7-bromo-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 7-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 7-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 7-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 7-chloro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 7-chloro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 7-chloro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 7-fluoro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 7-fluoro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 7-fluoro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 7-fluoro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 7-fluoro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 7-fluoro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 7-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 7-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 7-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 7-trifluoromethyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 7-trifluoromethyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 7-trifluoromethyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 8-(benzyloxy)-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 8-(benzyloxy)-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 8-(benzyloxy)-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 8-bromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 8-bromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 8-bromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 8-bromo-7-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 8-bromo-7-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 8-bromo-7-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione potent inhibitor Homo sapiens
1.4.3.3 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione potent inhibitor Rattus norvegicus
1.4.3.3 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione potent inhibitor Sus scrofa
1.4.3.3 8-ethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 8-ethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 8-ethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 8-ethyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 8-ethyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 8-ethyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 8-isopropoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 8-isopropoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 8-isopropoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 8-methoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 8-methoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 8-methoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 8-phenoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 8-phenoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 8-phenoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 8-phenylethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 8-phenylethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 8-phenylethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 8-phenylpropoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 8-phenylpropoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 8-phenylpropoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 8-trifluoromethyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Homo sapiens
1.4.3.3 8-trifluoromethyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Rattus norvegicus
1.4.3.3 8-trifluoromethyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
-
 Sus scrofa
1.4.3.3 methyl 2,3-dioxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine-7-carboxylate
-
 Homo sapiens
1.4.3.3 methyl 2,3-dioxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine-7-carboxylate
-
 Rattus norvegicus
1.4.3.3 methyl 2,3-dioxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine-7-carboxylate
-
 Sus scrofa
1.4.3.3 quinoxaline-2,3-dione
-
 Homo sapiens
1.4.3.3 quinoxaline-2,3-dione
-
 Rattus norvegicus
1.4.3.3 quinoxaline-2,3-dione
-
 Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.3 Homo sapiens
-
-
-
1.4.3.3 Rattus norvegicus
-
-
-
1.4.3.3 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.3 kidney
-
 Sus scrofa
-
1.4.3.3 spinal cord
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.3 D-Ala + H2O + O2
-
 Homo sapiens pyruvate + NH3 + H2O2
-
 ?
1.4.3.3 D-Ala + H2O + O2
-
 Rattus norvegicus pyruvate + NH3 + H2O2
-
 ?
1.4.3.3 D-Ala + H2O + O2
-
 Sus scrofa pyruvate + NH3 + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.3 DAAO
-
 Homo sapiens
1.4.3.3 DAAO
-
 Rattus norvegicus
1.4.3.3 DAAO
-
 Sus scrofa

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.4.3.3 0.000043
-
 at pH 8.2 and 37°C Homo sapiens 3-hydroxyquinolin-2-one
1.4.3.3 0.00009
-
 at pH 8.2 and 37°C Rattus norvegicus 6-chlorobenzo[d]isoxazol-3-ol
1.4.3.3 0.000094
-
 at pH 8.2 and 37°C Rattus norvegicus 3-hydroxyquinolin-2-one
1.4.3.3 0.0001
-
 at pH 8.2 and 37°C Sus scrofa 3-hydroxyquinolin-2-one
1.4.3.3 0.00011
-
 at pH 8.2 and 37°C Homo sapiens 6-chlorobenzo[d]isoxazol-3-ol
1.4.3.3 0.00014
-
 at pH 8.2 and 37°C Rattus norvegicus 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00015
-
 at pH 8.2 and 37°C Rattus norvegicus 7-fluoro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00015
-
 at pH 8.2 and 37°C Sus scrofa 7-fluoro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00018
-
 at pH 8.2 and 37°C Sus scrofa 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00021
-
 at pH 8.2 and 37°C Sus scrofa 6-chlorobenzo[d]isoxazol-3-ol
1.4.3.3 0.00021
-
 at pH 8.2 and 37°C Homo sapiens 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00022
-
 at pH 8.2 and 37°C Sus scrofa 8-bromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00023
-
 at pH 8.2 and 37°C Homo sapiens 8-bromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00024
-
 at pH 8.2 and 37°C Sus scrofa 8-bromo-7-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00026
-
 at pH 8.2 and 37°C Sus scrofa 7-chloro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00034
-
 at pH 8.2 and 37°C Homo sapiens 7-fluoro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.0004
-
 at pH 8.2 and 37°C Sus scrofa 7-bromo-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00046
-
 at pH 8.2 and 37°C Sus scrofa 7-fluoro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00048
-
 at pH 8.2 and 37°C Sus scrofa 7-bromo-8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00052
-
 at pH 8.2 and 37°C Sus scrofa 8-trifluoromethyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00053
-
 at pH 8.2 and 37°C Sus scrofa 7,8-dibromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00063
-
 at pH 8.2 and 37°C Sus scrofa 8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00065
-
 at pH 8.2 and 37°C Sus scrofa 7,8-dichloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00113
-
 at pH 8.2 and 37°C Homo sapiens 7-chloro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00138
-
 at pH 8.2 and 37°C Homo sapiens 8-bromo-7-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00224
-
 at pH 8.2 and 37°C Rattus norvegicus 8-bromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.0024
-
 at pH 8.2 and 37°C Sus scrofa 8-ethyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00416
-
 at pH 8.2 and 37°C Rattus norvegicus 7-chloro-8-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.0057
-
 at pH 8.2 and 37°C Sus scrofa 1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.0067
-
 at pH 8.2 and 37°C Sus scrofa 7-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.00799
-
 at pH 8.2 and 37°C Rattus norvegicus 8-bromo-7-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.0124
-
 at pH 8.2 and 37°C Sus scrofa 7-bromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.0177
-
 at pH 8.2 and 37°C Sus scrofa 6-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.0203
-
 at pH 8.2 and 37°C Sus scrofa 6-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.0229
-
 at pH 8.2 and 37°C Sus scrofa 7-trifluoromethyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.0336
-
 at pH 8.2 and 37°C Sus scrofa quinoxaline-2,3-dione
1.4.3.3 0.0367
-
 at pH 8.2 and 37°C Sus scrofa 7-methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.0857
-
 at pH 8.2 and 37°C Sus scrofa 8-methoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.1
-
 at pH 8.2 and 37°C Sus scrofa 6-methoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.1
-
 at pH 8.2 and 37°C Sus scrofa 6-ethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.1
-
 at pH 8.2 and 37°C Sus scrofa 8-ethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.1
-
 at pH 8.2 and 37°C Sus scrofa 8-isopropoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.3
-
 at pH 8.2 and 37°C Sus scrofa 8-(benzyloxy)-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.3
-
 at pH 8.2 and 37°C Sus scrofa 8-phenylethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.3
-
 at pH 8.2 and 37°C Sus scrofa 8-phenylpropoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.3
-
 at pH 8.2 and 37°C Sus scrofa 6-(benzyloxy)-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 0.3
-
 at pH 8.2 and 37°C Sus scrofa 6-phenethoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
1.4.3.3 1
-
 at pH 8.2 and 37°C Sus scrofa methyl 2,3-dioxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine-7-carboxylate
1.4.3.3 1
-
 at pH 8.2 and 37°C Sus scrofa 2,3-dioxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine-7-carboxylic acid
1.4.3.3 1
-
 at pH 8.2 and 37°C Sus scrofa 8-phenoxy-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione