Literature summary extracted from

Kim, E.; Kim, C.; Kim, S.
Identification of two novel mutant ANS alleles responsible for inactivation of anthocyanidin synthase and failure of anthocyanin production in onion (Allium cepa L.) (2016), Euphytica, 212, 427-437 .

No PubMed abstract available

Protein Variants

EC Number	Protein Variants	Comment	Organism
1.14.20.4	G229R	inactive mutant enzyme	Allium cepa
1.14.20.4	S188L	inactive mutant enzyme	Allium cepa

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.20.4	Allium cepa	A2ICD1	-	-

General Information

EC Number	General Information	Comment	Organism
1.14.20.4	malfunction	two inactive alleles are reported: a mutant anthocyanidin synthase allele containing a 4-bp insertion at the end of exon1 is identified from yellow bulbs of the F2 population in which the DFR-A (dihydroflavonol 4-reductase) genotype is homozygous for an active allele. The 4-bp insertion causes a frame-shift mutation and results in creation of a premature stop codon at the start of exon2. This mutant anthocyanidin synthase allele is designated ANSPS allele. RT-PCR results show that transcripts of the ANSPS allele are almost undetectable in yellow F2 bulbs, implying the involvement of nonsense-mediated mRNA decay. Another inactive anthocyanidin synthase allele is identified from the light-red F1 populations showing complementation between DFR-A (dihydroflavonol 4-reductase) and anthocyanidin synthase genes. A critical amino acid change of the strictly conserved serine residue into leucine is found in this mutant allele designated ANSS188L	Allium cepa

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Release 2023.1 (January 2023)