EC Number | Cloned (Comment) | Organism |
---|---|---|
1.8.98.1 | expressed in Escherichia coli | Desulfovibrio vulgaris |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.8.7.3 | Zn2+ | required | Desulfovibrio vulgaris | |
1.8.98.1 | Zn2+ | subunit HdrB contains zinc | Desulfovibrio vulgaris |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.7.3 | reduced ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB + H+ | Desulfovibrio vulgaris | - |
oxidized ferredoxin [iron-sulfur] cluster + CoB + CoM | - |
? | |
1.8.7.3 | reduced ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB + H+ | Desulfovibrio vulgaris ATCC 29579 | - |
oxidized ferredoxin [iron-sulfur] cluster + CoB + CoM | - |
? | |
1.8.7.3 | reduced ferredoxin [iron-sulfur] cluster + DsrC-S-S-DsrC + H+ | Desulfovibrio vulgaris | - |
oxidized ferredoxin [iron-sulfur] cluster + DsrC + DsrC | - |
? | |
1.8.7.3 | reduced ferredoxin [iron-sulfur] cluster + DsrC-S-S-DsrC + H+ | Desulfovibrio vulgaris ATCC 29579 | - |
oxidized ferredoxin [iron-sulfur] cluster + DsrC + DsrC | - |
? | |
1.8.98.1 | coenzyme B-coenzyme M disulfide + dihydromethanophenazine | Desulfovibrio vulgaris | - |
coenzyme B + coenzyme M + methanophenazine | - |
? | |
1.8.98.1 | coenzyme B-coenzyme M disulfide + dihydromethanophenazine | Desulfovibrio vulgaris ATCC 29579 | - |
coenzyme B + coenzyme M + methanophenazine | - |
? | |
1.8.98.1 | DsrC protein disulfide + dihydromethanophenazine | Desulfovibrio vulgaris | - |
DsrC protein + methanophenazine | - |
r | |
1.8.98.1 | DsrC protein disulfide + dihydromethanophenazine | Desulfovibrio vulgaris ATCC 29579 | - |
DsrC protein + methanophenazine | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.6.5.2 | Desulfovibrio vulgaris | Q729F2 and Q729F1 and Q729F0 | Q729F2 i.e. subunit FlxA, Q729F1 i.e. subunit FlxB, Q729F0 i.e. subunits FlxCD | - |
1.6.5.2 | Desulfovibrio vulgaris Hildenborough | Q729F2 and Q729F1 and Q729F0 | Q729F2 i.e. subunit FlxA, Q729F1 i.e. subunit FlxB, Q729F0 i.e. subunits FlxCD | - |
1.8.7.3 | Desulfovibrio vulgaris | - |
- |
- |
1.8.7.3 | Desulfovibrio vulgaris ATCC 29579 | - |
- |
- |
1.8.98.1 | Desulfovibrio vulgaris | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.8.7.3 | Q-Sepharose column chromatography and Superdex 200 gel filtration | Desulfovibrio vulgaris |
1.8.98.1 | Q-Sepharose column chromatography and Superdex 200 gel filtration | Desulfovibrio vulgaris |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.7.3 | reduced ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB + H+ | - |
Desulfovibrio vulgaris | oxidized ferredoxin [iron-sulfur] cluster + CoB + CoM | - |
? | |
1.8.7.3 | reduced ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB + H+ | - |
Desulfovibrio vulgaris ATCC 29579 | oxidized ferredoxin [iron-sulfur] cluster + CoB + CoM | - |
? | |
1.8.7.3 | reduced ferredoxin [iron-sulfur] cluster + DsrC-S-S-DsrC + H+ | - |
Desulfovibrio vulgaris | oxidized ferredoxin [iron-sulfur] cluster + DsrC + DsrC | - |
? | |
1.8.7.3 | reduced ferredoxin [iron-sulfur] cluster + DsrC-S-S-DsrC + H+ | - |
Desulfovibrio vulgaris ATCC 29579 | oxidized ferredoxin [iron-sulfur] cluster + DsrC + DsrC | - |
? | |
1.8.98.1 | coenzyme B-coenzyme M disulfide + dihydromethanophenazine | - |
Desulfovibrio vulgaris | coenzyme B + coenzyme M + methanophenazine | - |
? | |
1.8.98.1 | coenzyme B-coenzyme M disulfide + dihydromethanophenazine | - |
Desulfovibrio vulgaris ATCC 29579 | coenzyme B + coenzyme M + methanophenazine | - |
? | |
1.8.98.1 | DsrC protein disulfide + dihydromethanophenazine | - |
Desulfovibrio vulgaris | DsrC protein + methanophenazine | - |
r | |
1.8.98.1 | DsrC protein disulfide + dihydromethanophenazine | - |
Desulfovibrio vulgaris ATCC 29579 | DsrC protein + methanophenazine | - |
r |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.6.5.2 | DVU_2399 | locus name, subunit FlxA | Desulfovibrio vulgaris |
1.6.5.2 | DVU_2400 | locus name, subunit FlxB | Desulfovibrio vulgaris |
1.6.5.2 | DVU_2401 | locus name, subunit FlxCD | Desulfovibrio vulgaris |
1.6.5.2 | FlxABCD | - |
Desulfovibrio vulgaris |
1.8.7.3 | HdrABC | - |
Desulfovibrio vulgaris |
1.8.7.3 | HdrB | subunit | Desulfovibrio vulgaris |
1.8.98.1 | HdrABC | - |
Desulfovibrio vulgaris |
1.8.98.1 | heterodisulfide reductase | - |
Desulfovibrio vulgaris |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.6.5.2 | FAD | flavoprotein subunit FlxA is involved in oxidation/reduction of NAD(P)H/NAD(P)+ | Desulfovibrio vulgaris | |
1.8.98.1 | FAD | - |
Desulfovibrio vulgaris |
EC Number | Organism | Comment | Expression |
---|---|---|---|
1.6.5.2 | Desulfovibrio vulgaris | expression increases during growth in ethanol-sulfate, and to a less extent during pyruvate fermentation | up |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.6.5.2 | physiological function | a gene disruption strain is unable to grow with ethanol-sulfate. The FlxABCD-HdrABC (heterodisulfide reductase) proteins are essential for NADH oxidation during growth on ethanol, while in fermentation they operate in reverse, reducing NAD+ for ethanol production | Desulfovibrio vulgaris |
1.8.98.1 | metabolism | the enzyme is involved in ethanol metabolism | Desulfovibrio vulgaris |