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Literature summary extracted from

  • Stiborova, M.; Indra, R.; Moserova, M.; Frei, E.; Schmeiser, H.H.; Kopka, K.; Philips, D.H.; Arlt, V.M.
    NADH cytochrome b5 reductase and cytochrome b5 can act as sole electron donors to human cytochrome P450 1A1-mediated oxidation and DNA adduct formation by benzo[a]pyrene (2016), Chem. Res. Toxicol., 29, 1325-1334 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.6.2.2 NADH + ferricytochrome b5 Rattus norvegicus
-
 NAD+ + H+ + ferrocytochrome b5
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.6.2.2 Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.6.2.2 NADH + ferricytochrome b5
-
 Rattus norvegicus NAD+ + H+ + ferrocytochrome b5
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.6.2.2 CBR
-
 Rattus norvegicus
1.6.2.2 NADH:cytochrome b5 reductase
-
 Rattus norvegicus

General Information

EC Number General Information Comment Organism
1.6.2.2 metabolism the NADH/cytochrome b5/enzyme system can act as the sole electron donor both for the first and second reduction of cytochrome P450 1A1 during the oxidation of benzo[a]pyrene in vitro Rattus norvegicus