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Literature summary extracted from

  • Izidoro, L.F.; Sobrinho, J.C.; Mendes, M.M.; Costa, T.R.; Grabner, A.N.; Rodrigues, V.M.; da Silva, S.L.; Zanchi, F.B.; Zuliani, J.P.; Fernandes, C.F.; Calderon, L.A.; Stabeli, R.G.; Soares, A.M.
    Snake venom L-amino acid oxidases trends in pharmacology and biochemistry (2014), BioMed Res. Int., 2014, 196754 .
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.4.3.2 0.023
-
 L-Trp pH and temperature not specified in the publication Gloydius ussuriensis
1.4.3.2 0.042
-
 L-Phe pH and temperature not specified in the publication Gloydius ussuriensis
1.4.3.2 0.05
-
 L-Phe pH and temperature not specified in the publication Calloselasma rhodostoma
1.4.3.2 0.051
-
 L-Phe pH and temperature not specified in the publication Naja oxiana
1.4.3.2 0.058
-
 L-Phe pH and temperature not specified in the publication Vipera berus berus
1.4.3.2 0.08
-
 L-Trp pH and temperature not specified in the publication Calloselasma rhodostoma
1.4.3.2 0.1
-
 L-Phe pH and temperature not specified in the publication Ophiophagus hannah
1.4.3.2 0.1
-
 L-Trp pH and temperature not specified in the publication Ophiophagus hannah
1.4.3.2 0.11
-
 L-Leu pH and temperature not specified in the publication Gloydius ussuriensis
1.4.3.2 0.147
-
 L-Trp pH and temperature not specified in the publication Naja oxiana
1.4.3.2 0.17
-
 L-Trp pH and temperature not specified in the publication Macrovipera lebetina
1.4.3.2 0.2
-
 L-Leu pH and temperature not specified in the publication Ophiophagus hannah
1.4.3.2 0.24
-
 L-Met pH and temperature not specified in the publication Calloselasma rhodostoma
1.4.3.2 0.27
-
 L-Trp pH and temperature not specified in the publication Bungarus fasciatus
1.4.3.2 0.286
-
 L-Met pH and temperature not specified in the publication Vipera berus berus
1.4.3.2 0.361
-
 L-Leu pH and temperature not specified in the publication Vipera berus berus
1.4.3.2 0.4
-
 L-Leu pH and temperature not specified in the publication Macrovipera lebetina
1.4.3.2 0.63
-
 L-Leu pH and temperature not specified in the publication Calloselasma rhodostoma
1.4.3.2 0.63
-
 L-Met pH and temperature not specified in the publication Ophiophagus hannah
1.4.3.2 0.65
-
 L-Met pH and temperature not specified in the publication Macrovipera lebetina
1.4.3.2 0.75
-
 L-Leu pH and temperature not specified in the publication Naja oxiana
1.4.3.2 0.88
-
 L-Met pH and temperature not specified in the publication Gloydius ussuriensis
1.4.3.2 0.885
-
 L-Met pH and temperature not specified in the publication Naja oxiana
1.4.3.2 0.97
-
 L-Leu pH and temperature not specified in the publication Lachesis muta
1.4.3.2 9.23
-
 L-Leu pH and temperature not specified in the publication Crotalus durissus cumanensis
1.4.3.2 15.03
-
 L-Met pH and temperature not specified in the publication Bungarus fasciatus
1.4.3.2 60.69
-
 L-Leu pH and temperature not specified in the publication Bungarus fasciatus
1.4.3.2 84.08
-
 L-Phe pH and temperature not specified in the publication Bungarus fasciatus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.4.3.2 L-Arg + H2O + O2 Macrovipera lebetina
-
 2-oxo-5-guanidinovaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Arg + H2O + O2 Bungarus fasciatus
-
 2-oxo-5-guanidinovaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Arg + H2O + O2 Bungarus caeruleus
-
 2-oxo-5-guanidinovaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Arg + H2O + O2 Vipera berus berus
-
 2-oxo-5-guanidinovaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Arg + H2O + O2 Aplysia punctata
-
 2-oxo-5-guanidinovaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Asp + H2O + O2 Bungarus fasciatus
-
 oxaloacetate + NH3 + H2O2
-
 ?
1.4.3.2 L-Glu + H2O + O2 Bungarus fasciatus
-
 2-oxoglutarate + NH3 + H2O2
-
 ?
1.4.3.2 L-Glu + H2O + O2 Bungarus caeruleus
-
 2-oxoglutarate + NH3 + H2O2
-
 ?
1.4.3.2 L-His + H2O + O2 Ophiophagus hannah
-
 2-oxo-4-imidazolepropionic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-His + H2O + O2 Macrovipera lebetina
-
 2-oxo-4-imidazolepropionic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-His + H2O + O2 Bothrops pirajai
-
 2-oxo-4-imidazolepropionic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-His + H2O + O2 Vipera berus berus
-
 2-oxo-4-imidazolepropionic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2 Bothrops atrox
-
 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2 Bothrops jararaca
-
 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2 Ophiophagus hannah
-
 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2 Macrovipera lebetina
-
 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2 Bungarus fasciatus
-
 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2 Bothrops pirajai
-
 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2 Bungarus caeruleus
-
 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2 Bothrops pauloensis
-
 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2 Vipera berus berus
-
 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Calloselasma rhodostoma
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Bothrops atrox
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Daboia russelii
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Bothrops jararaca
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Ophiophagus hannah
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Lachesis muta
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Naja oxiana
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Macrovipera lebetina
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Bungarus fasciatus
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Bothrops alternatus
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Bothrops pirajai
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Gloydius ussuriensis
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Bungarus caeruleus
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Bothrops pauloensis
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Crotalus durissus cumanensis
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Bothrops leucurus
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2 Vipera berus berus
-
 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Lys + H2O + O2 Ophiophagus hannah
-
 6-amino-2-oxo-hexanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Lys + H2O + O2 Aplysia punctata
-
 6-amino-2-oxo-hexanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2 Calloselasma rhodostoma
-
 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2 Bothrops atrox
-
 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2 Ophiophagus hannah
-
 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2 Naja oxiana
-
 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2 Macrovipera lebetina
-
 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2 Bungarus fasciatus
-
 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2 Bothrops alternatus
-
 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2 Bothrops pirajai
-
 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2 Gloydius ussuriensis
-
 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2 Bungarus caeruleus
-
 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2 Bothrops pauloensis
-
 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2 Vipera berus berus
-
 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2 Calloselasma rhodostoma
-
 phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2 Bothrops atrox
-
 phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2 Bothrops jararaca
-
 phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2 Ophiophagus hannah
-
 phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2 Naja oxiana
-
 phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2 Macrovipera lebetina
-
 phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2 Bungarus fasciatus
-
 phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2 Bothrops alternatus
-
 phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2 Bothrops pirajai
-
 phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2 Gloydius ussuriensis
-
 phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2 Bungarus caeruleus
-
 phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2 Bothrops pauloensis
-
 phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2 Vipera berus berus
-
 phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2 Calloselasma rhodostoma
-
 indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2 Bothrops atrox
-
 indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2 Ophiophagus hannah
-
 indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2 Naja oxiana
-
 indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2 Macrovipera lebetina
-
 indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2 Bungarus fasciatus
-
 indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2 Bothrops pirajai
-
 indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2 Gloydius ussuriensis
-
 indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2 Bungarus caeruleus
-
 indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Tyr + H2O + O2 Bothrops atrox
-
 4-hydroxyphenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Tyr + H2O + O2 Bothrops jararaca
-
 4-hydroxyphenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Tyr + H2O + O2 Bungarus fasciatus
-
 4-hydroxyphenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Tyr + H2O + O2 Bothrops alternatus
-
 4-hydroxyphenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Tyr + H2O + O2 Bothrops pirajai
-
 4-hydroxyphenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Val + H2O + O2 Bothrops pirajai
-
 2-oxoisovalerate + NH3 + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.2 Aplysia punctata
-
-
-
1.4.3.2 Bothrops alternatus
-
-
-
1.4.3.2 Bothrops atrox
-
-
-
1.4.3.2 Bothrops insularis
-
-
-
1.4.3.2 Bothrops jararaca
-
-
-
1.4.3.2 Bothrops leucurus
-
-
-
1.4.3.2 Bothrops marajoensis
-
-
-
1.4.3.2 Bothrops pauloensis
-
-
-
1.4.3.2 Bothrops pirajai
-
-
-
1.4.3.2 Bungarus caeruleus
-
-
-
1.4.3.2 Bungarus fasciatus
-
-
-
1.4.3.2 Calloselasma rhodostoma
-
-
-
1.4.3.2 Crotalus durissus cumanensis
-
-
-
1.4.3.2 Daboia russelii
-
-
-
1.4.3.2 Deinagkistrodon acutus
-
-
-
1.4.3.2 Gloydius ussuriensis
-
-
-
1.4.3.2 Lachesis muta
-
-
-
1.4.3.2 Macrovipera lebetina
-
-
-
1.4.3.2 Naja oxiana
-
-
-
1.4.3.2 Ophiophagus hannah
-
-
-
1.4.3.2 Vipera berus berus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.4.3.2 benzamidine-Sepharose and phenyl-Sepharose column chromatography Bothrops pirajai
1.4.3.2 CM-Sepharose column chromatography, phenyl-Sepharose CL-4B column chromatography, benzamidine Sepharose and C18 RP column chromatography Bothrops pauloensis
1.4.3.2 DEAE cellulose column chromatography and Sephadex G-100 gel filtration Bungarus caeruleus
1.4.3.2 DEAE Sepharose F column chromatography and Source 30 column chromatography Deinagkistrodon acutus
1.4.3.2 G-75 gel filtration, HPLC-Shodex ES-502N 7C column chromatography, and Lentil lectin column chromatography Bothrops atrox
1.4.3.2 HPLC AP1 column chromatography and Superdex 75 gel filtration Bothrops insularis
1.4.3.2 ion-exchange column chromatography, Sephadex G-75 gel filtration and C4 reverse phase protein pack SP 5PW chromatography Gloydius ussuriensis
1.4.3.2 Mono Q and heparin column chromatography Bothrops jararaca
1.4.3.2 Protein Pack SP 5PW anion exchange chromatography and Superdex 200 gel filtration Bothrops marajoensis
1.4.3.2 Sephacryl S-200 gel filtration, Sephacryl S-300 gel filtration, and DEAE Sepharose CL-6B column chromatography Bothrops leucurus
1.4.3.2 Sephacryl S200 column chromatography Crotalus durissus cumanensis
1.4.3.2 Sephacryl S200 gel filtration and MonoQ column chromatography Lachesis muta
1.4.3.2 Sephadex G-100 gel filtration, DEAE-cellulose column chromatography, and phenyl-agarose column chromatography Vipera berus berus
1.4.3.2 Sephadex G-100 gel filtration, HPS-7 column chromatography, DEAE-cellulose DE52 column chromatography, and CM-cellulose CM52 column chromatography Macrovipera lebetina
1.4.3.2 Sephadex G-100 gel filtration, Q column chromatography, and HiTrap heparin column chromatography Ophiophagus hannah
1.4.3.2 Sephadex G-50 SF gel filtration, CM-cellulose CM52 column chromatography, and HPS-7 column chromatography Naja oxiana
1.4.3.2 Sepharose-IDA column chromatography, phenyl-Sepharose column chromatography, and Sephadex G-100 gel filtration Bothrops alternatus
1.4.3.2 Source 15Q column chromatography and Superose 12 gel filtration Aplysia punctata
1.4.3.2 SP-Sepharose column chromatography and heparin-Sepharose column chromatography Bungarus fasciatus
1.4.3.2 Superdex 75 gel filtration, Mono Q column chromatography, and heparin-Sepharose column chromatography Daboia russelii

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.2 venom
-
 Calloselasma rhodostoma
-
1.4.3.2 venom
-
 Bothrops atrox
-
1.4.3.2 venom
-
 Bothrops marajoensis
-
1.4.3.2 venom
-
 Daboia russelii
-
1.4.3.2 venom
-
 Bothrops jararaca
-
1.4.3.2 venom
-
 Ophiophagus hannah
-
1.4.3.2 venom
-
 Lachesis muta
-
1.4.3.2 venom
-
 Naja oxiana
-
1.4.3.2 venom
-
 Macrovipera lebetina
-
1.4.3.2 venom
-
 Deinagkistrodon acutus
-
1.4.3.2 venom
-
 Bungarus fasciatus
-
1.4.3.2 venom
-
 Bothrops alternatus
-
1.4.3.2 venom
-
 Bothrops pirajai
-
1.4.3.2 venom
-
 Gloydius ussuriensis
-
1.4.3.2 venom
-
 Bungarus caeruleus
-
1.4.3.2 venom
-
 Bothrops insularis
-
1.4.3.2 venom
-
 Bothrops pauloensis
-
1.4.3.2 venom
-
 Crotalus durissus cumanensis
-
1.4.3.2 venom
-
 Bothrops leucurus
-
1.4.3.2 venom
-
 Vipera berus berus
-
1.4.3.2 venom
-
 Aplysia punctata
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.2 L-Arg + H2O + O2
-
 Macrovipera lebetina 2-oxo-5-guanidinovaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Arg + H2O + O2
-
 Bungarus fasciatus 2-oxo-5-guanidinovaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Arg + H2O + O2
-
 Bungarus caeruleus 2-oxo-5-guanidinovaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Arg + H2O + O2
-
 Vipera berus berus 2-oxo-5-guanidinovaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Arg + H2O + O2
-
 Aplysia punctata 2-oxo-5-guanidinovaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Asp + H2O + O2
-
 Bungarus fasciatus oxaloacetate + NH3 + H2O2
-
 ?
1.4.3.2 L-Glu + H2O + O2
-
 Bungarus fasciatus 2-oxoglutarate + NH3 + H2O2
-
 ?
1.4.3.2 L-Glu + H2O + O2
-
 Bungarus caeruleus 2-oxoglutarate + NH3 + H2O2
-
 ?
1.4.3.2 L-His + H2O + O2
-
 Ophiophagus hannah 2-oxo-4-imidazolepropionic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-His + H2O + O2
-
 Macrovipera lebetina 2-oxo-4-imidazolepropionic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-His + H2O + O2
-
 Bothrops pirajai 2-oxo-4-imidazolepropionic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-His + H2O + O2
-
 Vipera berus berus 2-oxo-4-imidazolepropionic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2
-
 Bothrops atrox 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2
-
 Bothrops jararaca 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2
-
 Ophiophagus hannah 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2
-
 Macrovipera lebetina 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2
-
 Bungarus fasciatus 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2
-
 Bothrops pirajai 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2
-
 Bungarus caeruleus 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2
-
 Bothrops pauloensis 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Ile + H2O + O2
-
 Vipera berus berus 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Calloselasma rhodostoma 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Bothrops atrox 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Daboia russelii 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Bothrops jararaca 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Ophiophagus hannah 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Lachesis muta 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Naja oxiana 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Macrovipera lebetina 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Bungarus fasciatus 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Bothrops alternatus 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Bothrops pirajai 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Gloydius ussuriensis 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Bungarus caeruleus 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Bothrops pauloensis 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Crotalus durissus cumanensis 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Bothrops leucurus 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Leu + H2O + O2
-
 Vipera berus berus 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Lys + H2O + O2
-
 Ophiophagus hannah 6-amino-2-oxo-hexanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Lys + H2O + O2
-
 Aplysia punctata 6-amino-2-oxo-hexanoic acid + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2
-
 Calloselasma rhodostoma 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2
-
 Bothrops atrox 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2
-
 Ophiophagus hannah 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2
-
 Naja oxiana 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2
-
 Macrovipera lebetina 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2
-
 Bungarus fasciatus 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2
-
 Bothrops alternatus 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2
-
 Bothrops pirajai 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2
-
 Gloydius ussuriensis 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2
-
 Bungarus caeruleus 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2
-
 Bothrops pauloensis 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Met + H2O + O2
-
 Vipera berus berus 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2
-
 Calloselasma rhodostoma phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2
-
 Bothrops atrox phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2
-
 Bothrops jararaca phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2
-
 Ophiophagus hannah phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2
-
 Naja oxiana phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2
-
 Macrovipera lebetina phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2
-
 Bungarus fasciatus phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2
-
 Bothrops alternatus phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2
-
 Bothrops pirajai phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2
-
 Gloydius ussuriensis phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2
-
 Bungarus caeruleus phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2
-
 Bothrops pauloensis phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Phe + H2O + O2
-
 Vipera berus berus phenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2
-
 Calloselasma rhodostoma indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2
-
 Bothrops atrox indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2
-
 Ophiophagus hannah indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2
-
 Naja oxiana indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2
-
 Macrovipera lebetina indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2
-
 Bungarus fasciatus indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2
-
 Bothrops pirajai indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2
-
 Gloydius ussuriensis indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Trp + H2O + O2
-
 Bungarus caeruleus indole-3-pyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Tyr + H2O + O2
-
 Bothrops atrox 4-hydroxyphenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Tyr + H2O + O2
-
 Bothrops jararaca 4-hydroxyphenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Tyr + H2O + O2
-
 Bungarus fasciatus 4-hydroxyphenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Tyr + H2O + O2
-
 Bothrops alternatus 4-hydroxyphenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Tyr + H2O + O2
-
 Bothrops pirajai 4-hydroxyphenylpyruvate + NH3 + H2O2
-
 ?
1.4.3.2 L-Val + H2O + O2
-
 Bothrops pirajai 2-oxoisovalerate + NH3 + H2O2
-
 ?

Subunits

EC Number Subunits Comment Organism
1.4.3.2 homodimer 2 * 28000, SDS-PAGE Deinagkistrodon acutus
1.4.3.2 homodimer 2 * 55000, SDS-PAGE Bungarus fasciatus
1.4.3.2 homodimer 2 * 55000, SDS-PAGE Bungarus caeruleus
1.4.3.2 homodimer 2 * 55000, SDS-PAGE Crotalus durissus cumanensis
1.4.3.2 homodimer 2 * 60000, SDS-PAGE Lachesis muta
1.4.3.2 homodimer 2 * 60000, SDS-PAGE Aplysia punctata
1.4.3.2 homodimer 2 * 64000, SDS-PAGE Ophiophagus hannah
1.4.3.2 homodimer 2 * 66000, SDS-PAGE Macrovipera lebetina
1.4.3.2 homodimer 2 * 66000, SDS-PAGE Bothrops alternatus
1.4.3.2 homodimer 2 * 66000, SDS-PAGE Bothrops pirajai
1.4.3.2 homodimer 2 * 72000, SDS-PAGE Bothrops marajoensis
1.4.3.2 homodimer 2 * 57000, SDS-PAGE Naja oxiana
1.4.3.2 homodimer 2 * 57000, SDS-PAGE Bothrops leucurus
1.4.3.2 homodimer 2 * 59000, SDS-PAGE Vipera berus berus
1.4.3.2 homodimer 2 * 67000, SDS-PAGE Bothrops atrox
1.4.3.2 homodimer 2 * 68000, SDS-PAGE Bothrops insularis
1.4.3.2 homodimer 2 * 65000, SDS-PAGE Gloydius ussuriensis
1.4.3.2 homodimer 2 * 65000, SDS-PAGE Bothrops pauloensis
1.4.3.2 homodimer 2 * 38200, SDS-PAGE Bothrops jararaca
1.4.3.2 homodimer 2 * 63600, SDS-PAGE Daboia russelii

Synonyms

EC Number Synonyms Comment Organism
1.4.3.2 ACTX-8
-
 Deinagkistrodon acutus
1.4.3.2 LAAO
-
 Calloselasma rhodostoma
1.4.3.2 LAAO
-
 Bothrops atrox
1.4.3.2 LAAO
-
 Bothrops marajoensis
1.4.3.2 LAAO
-
 Bothrops jararaca
1.4.3.2 LAAO
-
 Ophiophagus hannah
1.4.3.2 LAAO
-
 Lachesis muta
1.4.3.2 LAAO
-
 Naja oxiana
1.4.3.2 LAAO
-
 Macrovipera lebetina
1.4.3.2 LAAO
-
 Deinagkistrodon acutus
1.4.3.2 LAAO
-
 Bungarus fasciatus
1.4.3.2 LAAO
-
 Gloydius ussuriensis
1.4.3.2 LAAO
-
 Bothrops pauloensis
1.4.3.2 LAAO
-
 Crotalus durissus cumanensis
1.4.3.2 LAAO
-
 Bothrops leucurus
1.4.3.2 LAAO
-
 Vipera berus berus
1.4.3.2 LAAO
-
 Aplysia punctata
1.4.3.2 LAAO-I
-
 Bothrops alternatus
1.4.3.2 LAAOI
-
 Bothrops pirajai
1.4.3.2 LAO
-
 Daboia russelii
1.4.3.2 LAO
-
 Bungarus caeruleus
1.4.3.2 LAO
-
 Bothrops insularis

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.4.3.2 0.72
-
 L-Phe pH and temperature not specified in the publication Calloselasma rhodostoma
1.4.3.2 0.88
-
 L-Trp pH and temperature not specified in the publication Calloselasma rhodostoma
1.4.3.2 1.65
-
 L-Met pH and temperature not specified in the publication Calloselasma rhodostoma
1.4.3.2 1.8
-
 L-Leu pH and temperature not specified in the publication Crotalus durissus cumanensis
1.4.3.2 3.3
-
 L-Leu pH and temperature not specified in the publication Calloselasma rhodostoma
1.4.3.2 6.58
-
 L-Trp pH and temperature not specified in the publication Gloydius ussuriensis
1.4.3.2 17.18
-
 L-Phe pH and temperature not specified in the publication Naja oxiana
1.4.3.2 18.04
-
 L-Trp pH and temperature not specified in the publication Naja oxiana
1.4.3.2 24.13
-
 L-Met pH and temperature not specified in the publication Gloydius ussuriensis
1.4.3.2 28.5
-
 L-Phe pH and temperature not specified in the publication Vipera berus berus
1.4.3.2 32.1
-
 L-Trp pH and temperature not specified in the publication Ophiophagus hannah
1.4.3.2 42.65
-
 L-Trp pH and temperature not specified in the publication Macrovipera lebetina
1.4.3.2 47.98
-
 L-Leu pH and temperature not specified in the publication Naja oxiana
1.4.3.2 48.22
-
 L-Leu pH and temperature not specified in the publication Gloydius ussuriensis
1.4.3.2 48.23
-
 L-Phe pH and temperature not specified in the publication Gloydius ussuriensis
1.4.3.2 52
-
 L-Leu pH and temperature not specified in the publication Macrovipera lebetina
1.4.3.2 54.1
-
 L-Phe pH and temperature not specified in the publication Ophiophagus hannah
1.4.3.2 65.6
-
 L-Met pH and temperature not specified in the publication Ophiophagus hannah
1.4.3.2 66.26
-
 L-Met pH and temperature not specified in the publication Naja oxiana
1.4.3.2 74.2
-
 L-Met pH and temperature not specified in the publication Vipera berus berus
1.4.3.2 75.16
-
 L-Leu pH and temperature not specified in the publication Vipera berus berus
1.4.3.2 80.3
-
 L-Met pH and temperature not specified in the publication Macrovipera lebetina
1.4.3.2 96.2
-
 L-Leu pH and temperature not specified in the publication Ophiophagus hannah
1.4.3.2 98.82
-
 L-Trp pH and temperature not specified in the publication Bungarus fasciatus
1.4.3.2 142.62
-
 L-Phe pH and temperature not specified in the publication Bungarus fasciatus
1.4.3.2 589.93
-
 L-Met pH and temperature not specified in the publication Bungarus fasciatus
1.4.3.2 1025.05
-
 L-Leu pH and temperature not specified in the publication Bungarus fasciatus

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.3.2 FAD
-
 Calloselasma rhodostoma
1.4.3.2 FAD
-
 Bothrops atrox
1.4.3.2 FAD
-
 Bothrops marajoensis
1.4.3.2 FAD
-
 Daboia russelii
1.4.3.2 FAD
-
 Bothrops jararaca
1.4.3.2 FAD
-
 Ophiophagus hannah
1.4.3.2 FAD
-
 Lachesis muta
1.4.3.2 FAD
-
 Naja oxiana
1.4.3.2 FAD
-
 Macrovipera lebetina
1.4.3.2 FAD
-
 Deinagkistrodon acutus
1.4.3.2 FAD
-
 Bungarus fasciatus
1.4.3.2 FAD
-
 Bothrops alternatus
1.4.3.2 FAD
-
 Bothrops pirajai
1.4.3.2 FAD
-
 Gloydius ussuriensis
1.4.3.2 FAD
-
 Bungarus caeruleus
1.4.3.2 FAD
-
 Bothrops insularis
1.4.3.2 FAD
-
 Bothrops pauloensis
1.4.3.2 FAD
-
 Crotalus durissus cumanensis
1.4.3.2 FAD
-
 Bothrops leucurus
1.4.3.2 FAD
-
 Vipera berus berus
1.4.3.2 FAD
-
 Aplysia punctata

pI Value

EC Number Organism Comment pI Value Maximum pI Value
1.4.3.2 Bothrops atrox isoelectric focusing
-
 4.4
1.4.3.2 Macrovipera lebetina isoelectric focusing
-
 4.5
1.4.3.2 Aplysia punctata isoelectric focusing
-
 4.6
1.4.3.2 Vipera berus berus isoelectric focusing
-
 4.8
1.4.3.2 Bothrops pirajai isoelectric focusing
-
 4.9
1.4.3.2 Bothrops alternatus isoelectric focusing
-
 5.4
1.4.3.2 Lachesis muta isoelectric focusing
-
 6.3
1.4.3.2 Bothrops pauloensis isoelectric focusing
-
 6.3
1.4.3.2 Naja oxiana isoelectric focusing
-
 8
1.4.3.2 Crotalus durissus cumanensis isoelectric focusing
-
 8
1.4.3.2 Deinagkistrodon acutus isoelectric focusing
-
 8.2

General Information

EC Number General Information Comment Organism
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Calloselasma rhodostoma
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Bothrops atrox
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Bothrops marajoensis
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Daboia russelii
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Bothrops jararaca
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Ophiophagus hannah
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Lachesis muta
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Naja oxiana
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Macrovipera lebetina
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Deinagkistrodon acutus
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Bungarus fasciatus
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Bothrops alternatus
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Bothrops pirajai
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Gloydius ussuriensis
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Bungarus caeruleus
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Bothrops insularis
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Bothrops pauloensis
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Bothrops leucurus
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Vipera berus berus
1.4.3.2 physiological function the enzyme exhibits cytotoxic, bactericidal, leishmanicidal, and antiviral effects Aplysia punctata