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Literature summary extracted from

  • Schenck, C.A.; Chen, S.; Siehl, D.L.; Maeda, H.A.
    Non-plastidic, tyrosine-insensitive prephenate dehydrogenases from legumes (2015), Nat. Chem. Biol., 11, 52-57.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.1.13 additional information not inhibited by L-Tyr Glycine max
1.3.1.13 additional information not inhibited by L-Tyr Medicago truncatula

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3.1.13 0.127
-
 prephenate at 37°C, pH not specified in the publication Glycine max
1.3.1.13 0.223
-
 prephenate at 37°C, pH not specified in the publication Medicago truncatula

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.1.13 prephenate + NADP+ Glycine max
-
 4-hydroxyphenylpyruvate + CO2 + NADPH
-
 ?
1.3.1.13 prephenate + NADP+ Medicago truncatula
-
 4-hydroxyphenylpyruvate + CO2 + NADPH
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.13 Glycine max
-
-
-
1.3.1.13 Medicago truncatula
-
-
-
1.3.1.13 no activity in Arabidopsis thaliana
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.1.13 leaf
-
 Glycine max
-
1.3.1.13 leaf
-
 Medicago truncatula
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.13 prephenate + NADP+
-
 Glycine max 4-hydroxyphenylpyruvate + CO2 + NADPH
-
 ?
1.3.1.13 prephenate + NADP+
-
 Medicago truncatula 4-hydroxyphenylpyruvate + CO2 + NADPH
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.1.13 PDH1
-
 Glycine max
1.3.1.13 PDH1
-
 Medicago truncatula
1.3.1.13 TyrAp
-
 Glycine max
1.3.1.13 TyrAp
-
 Medicago truncatula

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.3.1.13 21.8
-
 prephenate at 37°C, pH not specified in the publication Medicago truncatula
1.3.1.13 26.3
-
 prephenate at 37°C, pH not specified in the publication Glycine max

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.13 NADP+
-
 Glycine max
1.3.1.13 NADP+
-
 Medicago truncatula

kcat/KM [mM/s]

EC Number kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
1.3.1.13 100
-
 prephenate at 37°C, pH not specified in the publication Medicago truncatula
1.3.1.13 217
-
 prephenate at 37°C, pH not specified in the publication Glycine max