Literature summary extracted from

Fey, J.; Balleininger, M.; Borissenko, L.V.; Schmidt, B.; von Figura, K.; Dierks, T.
Characterization of posttranslational formylglycine formation by luminal components of the endoplasmic reticulum (2001), J. Biol.Chem., 276, 47021-47028.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
1.8.3.7	GSH	1 mM, activation	Bos taurus

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.8.3.7	GSSG	1 mM, inhibition	Bos taurus
1.8.3.7	PVSLCTPSRAALLTGR	-	Bos taurus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
1.8.3.7	endoplasmic reticulum	luminal side	Bos taurus	5783	-

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
1.8.3.7	Ca2+	activation	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.8.3.7	Bos taurus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.8.3.7	pancreas	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.8.3.7	[arylsulfatase A]-L-cysteine69 + O2 + reduced acceptor	-	Bos taurus	[arylsulfatase A]-Calpha-formylglycine69 + hydrogen sulfide + acceptor	-	?

Temperature Optimum [°C]

EC Number	Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
1.8.3.7	37	-	-	Bos taurus

Temperature Stability [°C]

EC Number	Temperature Stability Minimum [°C]	Temperature Stability Maximum [°C]	Comment	Organism
1.8.3.7	43	-	inactivation above	Bos taurus

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
1.8.3.7	10	10.7	-	Bos taurus

pH Range

EC Number	pH Minimum	pH Maximum	Comment	Organism
1.8.3.7	7	11	-	Bos taurus

IC50 Value

EC Number	IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
1.8.3.7	0.000134	-	pH 7.5, 37°C	Bos taurus	PVSLCTPSRAALLTGR

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Release 2023.1 (January 2023)