Literature summary extracted from

Shigi, N.; Sakaguchi, Y.; Suzuki, T.; Watanabe, K.
Identification of two tRNA thiolation genes required for cell growth at extremely high temperatures (2006), J. Biol. Chem., 281, 14296-14306.

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.8.1.15	Thermus thermophilus	Q72LF3	-	-
2.8.1.15	Thermus thermophilus DSM 7039	Q72LF3	-	-

Synonyms

EC Number	Synonyms	Comment	Organism
2.8.1.15	TTC0106	-	Thermus thermophilus
2.8.1.15	TtuA	-	Thermus thermophilus

General Information

EC Number	General Information	Comment	Organism
2.8.1.15	physiological function	mutation of either gene TtuA or TtuB completely abolishes thio-modification of 2-thioribothymidine, and the mutants exhibit a temperature-sensitive phenotype. TtuA is possibly an ATPase possessing a P-loop motif. TtuB is a putative thio-carrier protein. Both TtuA and TtuB are required for 2-thioribothymidine in vitro formation in the presence of cysteine and ATP	Thermus thermophilus

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Release 2023.1 (January 2023)