Literature summary extracted from

Kwon, S.; Bang, W.; Jeong, J.; Cho, H.; Park, D.; Hwang, J.; Kim, T.; Ko, M.; Cho, I.; Joo, Y.; Jeong, M.; Kim, S.; Kim, C.
Important role of the C-terminal region of pig aldo-keto reductase family 1 member C1 in the NADPH-dependent reduction of steroid hormones (2013), Indian J. Biochem. Biophys., 50, 237-241.

Protein Variants

EC Number	Protein Variants	Comment	Organism
1.1.1.149	additional information	a deletion mutant lacking residues R320 to L337 shows higher conversion rates of steroid hormones than wild-type. Especially 5alpha-dihydrotestosterone is more readily reduced	Sus scrofa

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.149	Sus scrofa	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.149	5alpha-dihydrotestosterone + NADPH + H+	-	Sus scrofa	? + NADP+	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.1.1.149	AKR1C1	-	Sus scrofa
1.1.1.149	aldo-keto reductase family 1 member C1	-	Sus scrofa

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Release 2023.1 (January 2023)