EC Number | Cloned (Comment) | Organism |
---|---|---|
1.1.1.71 | expressed in Sf9 insect cells | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.1.1.71 | membrane | integral-membrane protein | Homo sapiens | 16020 | - |
1.1.1.71 | microsome | - |
Homo sapiens | - |
- |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.1.1.71 | 36000 | - |
x * 36000, SDS-PAGE | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.71 | all-trans-retinal + NADPH + H+ | Homo sapiens | - |
all-trans-retinol + NADP+ | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.71 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.1.1.71 | HisTrap column chromatography, and Superdex 200 gel filtration | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.71 | adrenal gland | - |
Homo sapiens | - |
1.1.1.71 | kidney | - |
Homo sapiens | - |
1.1.1.71 | additional information | no or very low expression in lungs, spleen, pancreas, large intestine and eye | Homo sapiens | - |
1.1.1.71 | retina | - |
Homo sapiens | - |
1.1.1.71 | stomach | - |
Homo sapiens | - |
1.1.1.71 | thyroid gland | highest expression | Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.71 | 4-androstene-3,17-dione + NADPH + H+ | - |
Homo sapiens | ? | - |
? | |
1.1.1.71 | 4-methylnitrosamino-1-(3-pyridyl)-1-butanone + NADPH + H+ | - |
Homo sapiens | ? | - |
? | |
1.1.1.71 | 4-nitroacetophenone + NADPH + H+ | - |
Homo sapiens | ? | - |
? | |
1.1.1.71 | acetohexamide + NADPH + H+ | - |
Homo sapiens | ? | - |
? | |
1.1.1.71 | all-trans-retinal + NADPH + H+ | - |
Homo sapiens | all-trans-retinol + NADP+ | - |
? | |
1.1.1.71 | DL-glyceraldehyde + NADPH + H+ | - |
Homo sapiens | ? | - |
? | |
1.1.1.71 | estrone + NADPH + H+ | - |
Homo sapiens | ? | - |
? | |
1.1.1.71 | additional information | 4-nitroacetophenone, benzyl, cortisone and progesterone are no substrates | Homo sapiens | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.1.1.71 | ? | x * 36000, SDS-PAGE | Homo sapiens |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.1.1.71 | ADH | - |
Homo sapiens |
1.1.1.71 | DHRS3 | - |
Homo sapiens |
1.1.1.71 | retinal short-chain dehydrogenase/reductase member 3 | - |
Homo sapiens |
1.1.1.71 | retSDR1 | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.71 | NADPH | the enzyme prefers NADPH as a cofactor | Homo sapiens |