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Literature summary extracted from

  • LaMattina, J.; Delrossi, M.; Uy, K.; Keul, N.; Nix, D.; Neelam, A.; Lanzilotta, W.
    Anaerobic heme degradation: ChuY is an anaerobilin reductase that exhibits kinetic cooperativity (2017), Biochemistry, 56, 845-855.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.342 Escherichia coli
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Synonyms

EC Number Synonyms Comment Organism
2.1.1.342 chuW
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Escherichia coli

General Information

EC Number General Information Comment Organism
2.1.1.342 physiological function the oxygen-independent heme degradation pathway of Escherichia coli O157:H7 consists of ChuW, a radical SAM methyltransferase, which methylates heme to form the linear tetrapyrrole anaerobilin and liberate iron. ChuY uses anaerobilin as a substrate, reducing it to the tetrapyrrole termed anaerorubin Escherichia coli