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Literature summary extracted from

  • Rohatgi, N.; Nielsen, T.; Bjorn, S.; Axelsson, I.; Paglia, G.; Voldborg, B.; Palsson, B.; Rolfsson, O.
    Biochemical characterization of human gluconokinase and the proposed metabolic impact of gluconic acid as determined by constraint based metabolic network analysis (2014), PLoS ONE, 9, e98760.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.12 expression in Escherichia coli Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.12 0.106
-
D-gluconate pH 7.2, temperature not specified in the publication Homo sapiens
2.7.1.12 0.344
-
ATP pH 7.2, temperature not specified in the publication Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.1.12 21800
-
-
Homo sapiens
2.7.1.12 41800
-
PAGE Homo sapiens
2.7.1.12 85000
-
PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.12 Homo sapiens Q5T6J7
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.12 ATP + D-gluconate
-
Homo sapiens ADP + 6-phospho-D-gluconate
-
?
2.7.1.12 ATP + D-glucono-1,5-lactone
-
Homo sapiens ADP + 6-phospho-D-glucono-1,5-lactone
-
?
2.7.1.12 CTP + D-gluconate
-
Homo sapiens CDP + 6-phospho-D-gluconate
-
?
2.7.1.12 GTP + D-gluconate
-
Homo sapiens GDP + 6-phospho-D-gluconate
-
?
2.7.1.12 additional information no substrates: D-glucose, D-galactose, D-fructose, D-mannose and D-glucosamine, D-ribose, D-ribulose, D-arabinose, D-xylulose, D-xylose and D-erythrose Homo sapiens ?
-
?
2.7.1.12 UTP + D-gluconate
-
Homo sapiens UDP + 6-phospho-D-gluconate
-
?

Subunits

EC Number Subunits Comment Organism
2.7.1.12 dimer and tetramer, 2 * 23326, calculated, 2 * 21800, SDS-PAGE Homo sapiens
2.7.1.12 tetramer and dimer, 4 * 23326, calculated, 4 * 21800, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.7.1.12 C9orf103
-
Homo sapiens
2.7.1.12 gntK
-
Homo sapiens
2.7.1.12 IdnK
-
Homo sapiens

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.7.1.12 9.3
-
D-gluconate pH 7.2, temperature not specified in the publication Homo sapiens
2.7.1.12 9.5
-
ATP pH 7.2, temperature not specified in the publication Homo sapiens

kcat/KM [mM/s]

EC Number kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
2.7.1.12 28
-
ATP pH 7.2, temperature not specified in the publication Homo sapiens
2.7.1.12 89
-
D-gluconate pH 7.2, temperature not specified in the publication Homo sapiens