EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.4.2.45 | A35E | the mutant is associated with high-level ethambutol resistance and increases decaprenylphosphoryl-beta-D-arabinose levels | Mycobacterium tuberculosis |
2.4.2.45 | G165C | the mutant is associated with high-level ethambutol resistance and increases decaprenylphosphoryl-beta-D-arabinose levels | Mycobacterium tuberculosis |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.2.45 | ethambutol | - |
Mycobacterium tuberculosis |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.2.45 | trans,octacis-decaprenyl phosphate + 5-phospho-alpha-D-ribose 1-diphosphate | Mycobacterium tuberculosis | - |
trans,octacis-decaprenylphospho-beta-D-ribofuranose 5-phosphate + diphosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.2.45 | Mycobacterium tuberculosis | P9WFR5 | - |
- |
2.4.2.46 | Mycobacterium tuberculosis | P9WN03 | - |
- |
2.4.2.46 | Mycobacterium tuberculosis H37Rv | P9WN03 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.2.45 | trans,octacis-decaprenyl phosphate + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Mycobacterium tuberculosis | trans,octacis-decaprenylphospho-beta-D-ribofuranose 5-phosphate + diphosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.2.45 | 5-phospho-alpha-FS18 D-ribose-1-diphosphate:decaprenyl-phosphate 5-phosphoribosyltransferase | - |
Mycobacterium tuberculosis |
2.4.2.45 | DPPR synthase | - |
Mycobacterium tuberculosis |
2.4.2.45 | Rv3806 | - |
Mycobacterium tuberculosis |
2.4.2.45 | ubiA | - |
Mycobacterium tuberculosis |
2.4.2.46 | AftA | - |
Mycobacterium tuberculosis |
2.4.2.46 | arabinofuranosyltransferase | - |
Mycobacterium tuberculosis |
2.4.2.46 | Rv3792 | - |
Mycobacterium tuberculosis |