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Literature summary extracted from

  • Endoh, T.; Habe, H.; Nojiri, H.; Yamane, H.; Omori, T.
    The sigma54-dependent transcriptional activator SfnR regulates the expression of the Pseudomonas putida sfnFG operon responsible for dimethyl sulphone utilization (2005), Mol. Microbiol., 55, 897-911.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.14.35 expression in Escherichia coli Pseudomonas putida

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.35 Pseudomonas putida Q65YW9
-
-
1.14.14.35 Pseudomonas putida DS1 Q65YW9
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.35 dimethyl sulfone + FMNH2 + O2
-
 Pseudomonas putida methanesulfinate + formaldehyde + FMN + H2O
-
 ?
1.14.14.35 dimethyl sulfone + FMNH2 + O2
-
 Pseudomonas putida DS1 methanesulfinate + formaldehyde + FMN + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.35 sfnG
-
 Pseudomonas putida

Expression

EC Number Organism Comment Expression
1.14.14.35 Pseudomonas putida expression of the sfnFG operon is directly activated by the binding of sigma54-dependent transcriptional activator SfnR at its upstream region additional information

General Information

EC Number General Information Comment Organism
1.14.14.35 physiological function the sfnG product is essential for dimethyl sulfone utilization by Pseudomonas putida DS1. SfnG is an FMNH2-dependent DMSO2 monooxygenase that converts DMSO2 to methanesulfinate. A SfnG mutant is still able to utilize methionine sulfone as a sulfur source Pseudomonas putida