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Literature summary extracted from

  • Narrandes, N.C.; Machowski, E.E.; Mizrahi, V.; Kana, B.D.
    Cleavage of the moaX-encoded fused molybdopterin synthase from Mycobacterium tuberculosis is necessary for activity (2015), BMC Microbiol., 15, 22.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.8.1.12 expressed in Escherichia coli BL21(DE3) cells Mycobacterium tuberculosis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.8.1.12 10000
-
-
 Mycobacterium tuberculosis
2.8.1.12 17000
-
-
 Mycobacterium tuberculosis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.1.12 cyclic pyranopterin phosphate + [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH2-C(O)SH + H2O Mycobacterium tuberculosis
-
 molybdopterin + molybdopterin-synthase sulfur-carrier protein
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.8.1.12 Mycobacterium tuberculosis Q6MWY3 carrier subunit MoaX
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.1.12 cyclic pyranopterin phosphate + [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH2-C(O)SH + H2O
-
 Mycobacterium tuberculosis molybdopterin + molybdopterin-synthase sulfur-carrier protein
-
 ?

Subunits

EC Number Subunits Comment Organism
2.8.1.12 heterotetramer 2 * 17000 + 2 * 10000, SDS-PAGE Mycobacterium tuberculosis

Synonyms

EC Number Synonyms Comment Organism
2.8.1.12 MoaD subunit Mycobacterium tuberculosis
2.8.1.12 MoaE catalytic subunit Mycobacterium tuberculosis
2.8.1.12 MoaX carrier subunit Mycobacterium tuberculosis
2.8.1.12 MPT synthase
-
 Mycobacterium tuberculosis
2.8.1.12 Rv3323c
-
 Mycobacterium tuberculosis