Literature summary extracted from

Youn, H.S.; Kim, M.K.; Kang, G.B.; Kim, T.G.; Lee, J.G.; An, J.Y.; Park, K.R.; Lee, Y.; Kang, J.Y.; Song, H.E.; Park, I.; Cho, C.; Fukuoka, S.; Eom, S.H.
Crystal structure of Sus scrofa quinolinate phosphoribosyltransferase in complex with nicotinate mononucleotide (2013), PLoS ONE, 8, e62027.

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
2.4.2.19	in complex with nicotinate mononucleotide, hanging drop vapor diffusion method, using 100 mM Tris-HCl, pH 8.0, 16-24% (w/v) PEG 8000, 150-200 mM ammonium acetate	Sus scrofa

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
2.4.2.19	33000	-	6 * 33000, X-ray crystallography	Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.4.2.19	beta-nicotinate D-ribonucleotide + diphosphate + CO2	Sus scrofa	-	pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.2.19	Sus scrofa	M1KCW7	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
2.4.2.19	ammonium sulfate precipitation and DEAE-Sephadex A-50 gel filtration	Sus scrofa

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.4.2.19	kidney	-	Sus scrofa	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.4.2.19	beta-nicotinate D-ribonucleotide + diphosphate + CO2	-	Sus scrofa	pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate	-	?

Subunits

EC Number	Subunits	Comment	Organism
2.4.2.19	hexamer	6 * 33000, X-ray crystallography	Sus scrofa

Synonyms

EC Number	Synonyms	Comment	Organism
2.4.2.19	QAPRTase	-	Sus scrofa
2.4.2.19	quinolinate phosphoribosyltransferase	-	Sus scrofa

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)