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Literature summary extracted from

  • Bhat, N.; Wojczyk, B.S.; DeCicco, M.; Castrodad, C.; Spitalnik, S.L.; Ward, H.D.
    Identification of a family of four UDP-polypeptide N-acetylgalactosaminyl transferases in Cryptosporidium species (2013), Mol. Biochem. Parasitol., 191, 24-27.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
2.4.1.41 medicine the enzyme serves as targets for intervention in cryptosporidiosis Cryptosporidium parvum
2.4.1.41 medicine the enzyme serves as targets for intervention in cryptosporidiosis Cryptosporidium hominis
2.4.1.41 medicine the enzyme serves as targets for intervention in cryptosporidiosis Cryptosporidium muris

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.41 membrane
-
 Cryptosporidium parvum 16020
-
2.4.1.41 membrane
-
 Cryptosporidium hominis 16020
-
2.4.1.41 membrane
-
 Cryptosporidium muris 16020
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.41 Cryptosporidium hominis
-
-
-
2.4.1.41 Cryptosporidium muris
-
-
-
2.4.1.41 Cryptosporidium parvum
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.41 sporozoite
-
 Cryptosporidium parvum
-
2.4.1.41 sporozoite
-
 Cryptosporidium hominis
-
2.4.1.41 sporozoite
-
 Cryptosporidium muris
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.41 additional information almost no activity with polypeptides biotin-EA2-7, biotin-MUC5AC, and no activity with polypeptide MUC5AC-biotin Cryptosporidium parvum ?
-
 ?
2.4.1.41 additional information almost no activity with polypeptides biotin-EA2-7, biotin-MUC5AC, and no activity with polypeptide MUC5AC-biotin Cryptosporidium hominis ?
-
 ?
2.4.1.41 additional information almost no activity with polypeptides biotin-EA2-7, biotin-MUC5AC, and no activity with polypeptide MUC5AC-biotin Cryptosporidium muris ?
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide biotin-EA2 sequence biotin-PTTDSTTPAPTTK, second highest activity Cryptosporidium parvum UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide biotin-EA2
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide biotin-EA2 sequence biotin-PTTDSTTPAPTTK, second highest activity Cryptosporidium hominis UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide biotin-EA2
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide biotin-EA2 sequence biotin-PTTDSTTPAPTTK, second highest activity Cryptosporidium muris UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide biotin-EA2
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide biotin-EA2-2 sequence biotin-PTTDSTTPAPTTK Cryptosporidium parvum UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide biotin-EA2-2
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide biotin-EA2-2 sequence biotin-PTTDSTTPAPTTK Cryptosporidium hominis UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide biotin-EA2-2
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide biotin-EA2-2 sequence biotin-PTTDSTTPAPTTK Cryptosporidium muris UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide biotin-EA2-2
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide EA2-biotin sequence PTTDSTTPAPTTK-biotin Cryptosporidium parvum UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide EA2-biotin
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide EA2-biotin sequence PTTDSTTPAPTTK-biotin Cryptosporidium hominis UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide EA2-biotin
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide EA2-biotin sequence PTTDSTTPAPTTK-biotin Cryptosporidium muris UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide EA2-biotin
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide GRA2-biotin highest activity Cryptosporidium parvum UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide GRA2-biotin
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide GRA2-biotin highest activity Cryptosporidium hominis UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide GRA2-biotin
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide GRA2-biotin highest activity Cryptosporidium muris UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide GRA2-biotin
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide MUC5AC-3,13-biotin sequence biotin-GTTPSPVPTTSTTSAP Cryptosporidium parvum UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide MUC5AC-3,13-biotin
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide MUC5AC-3,13-biotin sequence biotin-GTTPSPVPTTSTTSAP Cryptosporidium hominis UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide MUC5AC-3,13-biotin
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide MUC5AC-3,13-biotin sequence biotin-GTTPSPVPTTSTTSAP Cryptosporidium muris UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide MUC5AC-3,13-biotin
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.41 ppGalNAc-T1 isoform Cryptosporidium parvum
2.4.1.41 ppGalNAc-T1 isoform Cryptosporidium hominis
2.4.1.41 ppGalNAc-T1 isoform Cryptosporidium muris
2.4.1.41 ppGalNAc-T2 isoform Cryptosporidium parvum
2.4.1.41 ppGalNAc-T2 isoform Cryptosporidium hominis
2.4.1.41 ppGalNAc-T2 isoform Cryptosporidium muris
2.4.1.41 ppGalNAc-T3 isoform Cryptosporidium parvum
2.4.1.41 ppGalNAc-T3 isoform Cryptosporidium hominis
2.4.1.41 ppGalNAc-T3 isoform Cryptosporidium muris
2.4.1.41 ppGalNAc-T4 isoform Cryptosporidium parvum
2.4.1.41 ppGalNAc-T4 isoform Cryptosporidium hominis
2.4.1.41 ppGalNAc-T4 isoform Cryptosporidium muris
2.4.1.41 UDP N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyl transferase
-
 Cryptosporidium muris
2.4.1.41 UDP N-acetyl-alpha-Dgalactosamine:polypeptide N-acetylgalactosaminyl transferase
-
 Cryptosporidium parvum
2.4.1.41 UDP N-acetyl-alpha-Dgalactosamine:polypeptide N-acetylgalactosaminyl transferase
-
 Cryptosporidium hominis
2.4.1.41 UDP-polypeptide N-acetylgalactosaminyl transferase
-
 Cryptosporidium parvum
2.4.1.41 UDP-polypeptide N-acetylgalactosaminyl transferase
-
 Cryptosporidium hominis
2.4.1.41 UDP-polypeptide N-acetylgalactosaminyl transferase
-
 Cryptosporidium muris