BRENDA - Enzyme Database

New plasmid-mediated aminoglycoside 6-N-acetyltransferase, AAC(6')-Ian, and ESBL, TLA-3, from a Serratia marcescens clinical isolate

Jin, W.; Wachino, J.; Kimura, K.; Yamada, K.; Arakawa, Y.; J. Antimicrob. Chemother. 70, 1331-1337 (2015)

Data extracted from this reference:

Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.3.1.82
Serratia marcescens
A0A0B6VRK1
-
-
2.3.1.82
Serratia marcescens NUBL-11663
A0A0B6VRK1
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.3.1.82
acetyl-CoA + amikacin
-
736322
Serratia marcescens
CoA + N6'-acetylamikacin
-
-
-
?
2.3.1.82
acetyl-CoA + amikacin
-
736322
Serratia marcescens NUBL-11663
CoA + N6'-acetylamikacin
-
-
-
?
2.3.1.82
acetyl-CoA + arbekacin
-
736322
Serratia marcescens
CoA + N6'-acetylarbekacin
-
-
-
?
2.3.1.82
acetyl-CoA + gentamicin
-
736322
Serratia marcescens
CoA + N6'-acetylgentamicin
-
-
-
?
2.3.1.82
acetyl-CoA + gentamicin
-
736322
Serratia marcescens NUBL-11663
CoA + N6'-acetylgentamicin
-
-
-
?
2.3.1.82
acetyl-CoA + isepamicin
-
736322
Serratia marcescens
CoA + 6'-N-acetylisepamicin
-
-
-
?
2.3.1.82
acetyl-CoA + kanamycin
-
736322
Serratia marcescens
CoA + N6'-acetylkanamycin
-
-
-
?
2.3.1.82
acetyl-CoA + kanamycin
-
736322
Serratia marcescens NUBL-11663
CoA + N6'-acetylkanamycin
-
-
-
?
2.3.1.82
acetyl-CoA + neomycin
-
736322
Serratia marcescens
CoA + N6'-acetylneomycin
-
-
-
?
2.3.1.82
acetyl-CoA + neomycin
-
736322
Serratia marcescens NUBL-11663
CoA + N6'-acetylneomycin
-
-
-
?
2.3.1.82
acetyl-CoA + netilmicin
-
736322
Serratia marcescens
CoA + 6'-N-acetylnetilmicin
-
-
-
?
2.3.1.82
acetyl-CoA + ribostamycin
-
736322
Serratia marcescens
CoA + 6'-N-acetylribostamycin
-
-
-
?
2.3.1.82
acetyl-CoA + sisomicin
-
736322
Serratia marcescens
CoA + 6'-N-acetylsisomicin
-
-
-
?
2.3.1.82
acetyl-CoA + tobramycin
-
736322
Serratia marcescens
CoA + 6'-N-acetyltobramycin
-
-
-
?
2.3.1.82
additional information
isoform AAC(6')-Ian acetylates 4,6- and 4,5-disubstituted 2-deoxystreptamine aminoglycosides
736322
Serratia marcescens
?
-
-
-
-
2.3.1.82
additional information
isoform AAC(6')-Ian acetylates 4,6- and 4,5-disubstituted 2-deoxystreptamine aminoglycosides
736322
Serratia marcescens NUBL-11663
?
-
-
-
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.3.1.82
acetyl-CoA + amikacin
-
736322
Serratia marcescens
CoA + N6'-acetylamikacin
-
-
-
?
2.3.1.82
acetyl-CoA + amikacin
-
736322
Serratia marcescens NUBL-11663
CoA + N6'-acetylamikacin
-
-
-
?
2.3.1.82
acetyl-CoA + arbekacin
-
736322
Serratia marcescens
CoA + N6'-acetylarbekacin
-
-
-
?
2.3.1.82
acetyl-CoA + gentamicin
-
736322
Serratia marcescens
CoA + N6'-acetylgentamicin
-
-
-
?
2.3.1.82
acetyl-CoA + gentamicin
-
736322
Serratia marcescens NUBL-11663
CoA + N6'-acetylgentamicin
-
-
-
?
2.3.1.82
acetyl-CoA + isepamicin
-
736322
Serratia marcescens
CoA + 6'-N-acetylisepamicin
-
-
-
?
2.3.1.82
acetyl-CoA + kanamycin
-
736322
Serratia marcescens
CoA + N6'-acetylkanamycin
-
-
-
?
2.3.1.82
acetyl-CoA + kanamycin
-
736322
Serratia marcescens NUBL-11663
CoA + N6'-acetylkanamycin
-
-
-
?
2.3.1.82
acetyl-CoA + neomycin
-
736322
Serratia marcescens
CoA + N6'-acetylneomycin
-
-
-
?
2.3.1.82
acetyl-CoA + neomycin
-
736322
Serratia marcescens NUBL-11663
CoA + N6'-acetylneomycin
-
-
-
?
2.3.1.82
acetyl-CoA + netilmicin
-
736322
Serratia marcescens
CoA + 6'-N-acetylnetilmicin
-
-
-
?
2.3.1.82
acetyl-CoA + ribostamycin
-
736322
Serratia marcescens
CoA + 6'-N-acetylribostamycin
-
-
-
?
2.3.1.82
acetyl-CoA + sisomicin
-
736322
Serratia marcescens
CoA + 6'-N-acetylsisomicin
-
-
-
?
2.3.1.82
acetyl-CoA + tobramycin
-
736322
Serratia marcescens
CoA + 6'-N-acetyltobramycin
-
-
-
?
2.3.1.82
additional information
isoform AAC(6')-Ian acetylates 4,6- and 4,5-disubstituted 2-deoxystreptamine aminoglycosides
736322
Serratia marcescens
?
-
-
-
-
2.3.1.82
additional information
isoform AAC(6')-Ian acetylates 4,6- and 4,5-disubstituted 2-deoxystreptamine aminoglycosides
736322
Serratia marcescens NUBL-11663
?
-
-
-
-