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Literature summary extracted from

  • Tsugehara, T.; Imai, T.; Takeda, M.
    Characterization of arylalkylamine N-acetyltransferase from silkmoth (Antheraea pernyi) and pesticidal drug design based on the baculovirus-expressed enzyme (2013), Comp. Biochem. Physiol. C, 157, 93-102.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.87 expression in Sf9 cell Antheraea pernyi

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.87 tryptamine inhibitory above 0.03 mM Antheraea pernyi

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.87 0.00142
-
 acetyl-CoA pH 7.4, 37°C Antheraea pernyi
2.3.1.87 0.00331
-
 tryptamine pH 7.4, 37°C Antheraea pernyi

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.87 32000
-
 x * 37000, SDS-PAGE, x * 32000, calculated Antheraea pernyi
2.3.1.87 37000
-
 x * 37000, SDS-PAGE, x * 32000, calculated Antheraea pernyi

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.87 Antheraea pernyi A2SZ52
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.87 brain the enzymatic activity is higher in adult than in pupal brain. No difference is observed between day and night in the pupal brain and adult brain Antheraea pernyi
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.87 acetyl-CoA + dopamine
-
 Antheraea pernyi CoA + N-acetyldopamine
-
 ?
2.3.1.87 acetyl-CoA + norepinephrine
-
 Antheraea pernyi CoA + N-acetylnorepinephrine
-
 ?
2.3.1.87 acetyl-CoA + octopamine
-
 Antheraea pernyi CoA + N-acetyloctopamine
-
 ?
2.3.1.87 acetyl-CoA + serotonin
-
 Antheraea pernyi CoA + N-acetylserotonin
-
 ?
2.3.1.87 acetyl-CoA + tryptamine
-
 Antheraea pernyi CoA + N-acetyltryptamine
-
 ?
2.3.1.87 acetyl-CoA + tyramine
-
 Antheraea pernyi CoA + N-acetyltyramine
-
 ?
2.3.1.87 additional information no substrate: sulfamethazine Antheraea pernyi ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.87 ? x * 37000, SDS-PAGE, x * 32000, calculated Antheraea pernyi

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.87 8
-
-
 Antheraea pernyi