Literature summary extracted from

Subrahmanyeswara Rao, N.; Deshpande, P.
An organism-independent unified model for activity of orotate phosphoribosyltransferases for orotidine monophosphate synthesis (2015), Chem. Eng. Sci., 128, 109-118.

No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.4.2.10	orotate + 5-phospho-alpha-D-ribose 1-diphosphate	Salmonella enterica subsp. enterica serovar Typhimurium	-	orotidine 5'-phosphate + diphosphate	-	r
2.4.2.10	orotate + 5-phospho-alpha-D-ribose 1-diphosphate	Saccharomyces cerevisiae	-	orotidine 5'-phosphate + diphosphate	-	r
2.4.2.10	orotate + 5-phospho-alpha-D-ribose 1-diphosphate	Mycobacterium tuberculosis	-	orotidine 5'-phosphate + diphosphate	-	r
2.4.2.10	orotate + 5-phospho-alpha-D-ribose 1-diphosphate	Plasmodium falciparum	-	orotidine 5'-phosphate + diphosphate	-	r

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.2.10	Mycobacterium tuberculosis	-	-	-
2.4.2.10	Plasmodium falciparum	-	-	-
2.4.2.10	Saccharomyces cerevisiae	-	-	-
2.4.2.10	Salmonella enterica subsp. enterica serovar Typhimurium	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.4.2.10	orotate + 5-phospho-alpha-D-ribose 1-diphosphate	-	Salmonella enterica subsp. enterica serovar Typhimurium	orotidine 5'-phosphate + diphosphate	-	r
2.4.2.10	orotate + 5-phospho-alpha-D-ribose 1-diphosphate	-	Saccharomyces cerevisiae	orotidine 5'-phosphate + diphosphate	-	r
2.4.2.10	orotate + 5-phospho-alpha-D-ribose 1-diphosphate	-	Mycobacterium tuberculosis	orotidine 5'-phosphate + diphosphate	-	r
2.4.2.10	orotate + 5-phospho-alpha-D-ribose 1-diphosphate	-	Plasmodium falciparum	orotidine 5'-phosphate + diphosphate	-	r

Synonyms

EC Number	Synonyms	Comment	Organism
2.4.2.10	OPRT	-	Salmonella enterica subsp. enterica serovar Typhimurium
2.4.2.10	OPRT	-	Saccharomyces cerevisiae
2.4.2.10	OPRT	-	Mycobacterium tuberculosis
2.4.2.10	OPRT	-	Plasmodium falciparum

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Release 2023.1 (January 2023)