EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.2.7.1 | copper | protein contains a copper-center | Pyrococcus furiosus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.2.7.1 | Pyrococcus furiosus | Q51804 and Q51805 and Q51803 and Q51799 | Q51804 i.e. subunit PorA, Q51805 i.e. subunit PorB, Q51803 i.e. subunit PorD, Q51799 i.e. subunit PorG | - |
1.2.7.1 | Thermotoga maritima | O05651 and Q56317 and O05650 and Q56316 | O05651 i.e. subunit PorA, Q56317 i.e. subunit PorB, O05650 i.e. subunit PorC, Q56316 i.e. subunit PorD | - |
1.2.7.1 | Thermotoga maritima DSM 3109 | O05651 and Q56317 and O05650 and Q56316 | O05651 i.e. subunit PorA, Q56317 i.e. subunit PorB, O05650 i.e. subunit PorC, Q56316 i.e. subunit PorD | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.7.1 | additional information | Incubation of the oxidized enzyme with CoA results in the partial reduction of a iron-sulfur center, which is not seen in the dithionite-reduced enzyme. Incubation of the oxidized enzyme with CoA results in the partial reduction of the copper site in POR. The addition of both pyruvate and CoA to the POR in its oxidized state results in the reduction of the same iron-sulfur center that is reduced by sodium dithionite | Thermotoga maritima | ? | - |
? | |
1.2.7.1 | additional information | the addition of pyruvate to oxidized POR produces an isotropic signal centered at g = 2.01, assigned to a (hydroxyethy1)thiamine pyrophosphate radical intermediate. Incubation of the oxidized enzyme with CoA results in the partial reduction of the copper site in POR. The addition of both pyruvate and CoA to the POR in its oxidized state results in the reduction of the same iron-sulfur center that is reduced by sodium dithionite | Pyrococcus furiosus | ? | - |
? | |
1.2.7.1 | additional information | Incubation of the oxidized enzyme with CoA results in the partial reduction of a iron-sulfur center, which is not seen in the dithionite-reduced enzyme. Incubation of the oxidized enzyme with CoA results in the partial reduction of the copper site in POR. The addition of both pyruvate and CoA to the POR in its oxidized state results in the reduction of the same iron-sulfur center that is reduced by sodium dithionite | Thermotoga maritima DSM 3109 | ? | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.2.7.1 | 80 | - |
- |
Thermotoga maritima |
1.2.7.1 | 100 | - |
- |
Pyrococcus furiosus |
EC Number | Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.2.7.1 | 25 | - |
inactive | Thermotoga maritima |
1.2.7.1 | 25 | - |
inactive | Pyrococcus furiosus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.2.7.1 | thiamine diphosphate | - |
Thermotoga maritima | |
1.2.7.1 | thiamine diphosphate | - |
Pyrococcus furiosus | |
1.2.7.1 | [4Fe-4S]-center | protein contains at least two [4Fe-4S] ferredoxin-type clusters | Thermotoga maritima | |
1.2.7.1 | [4Fe-4S]-center | protein contains at least two [4Fe-4S] ferredoxin-type clusters | Pyrococcus furiosus |