Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Maia, A.C.; Porcino, G.N.; Detoni, M.d.e..L.; Emidio, N.B.; Marconato, D.G.; Faria-Pinto, P.; Fessel, M.R.; Reis, A.B.; Juliano, L.; Juliano, M.A.; Marques, M.J.; Vasconcelos, E.G.
    An antigenic domain within a catalytically active Leishmania infantum nucleoside triphosphate diphosphohydrolase (NTPDase 1) is a target of inhibitory antibodies (2013), Parasitol. Int., 62, 44-52.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.5 EDTA complete inhibition at 5 mM Leishmania infantum
3.6.1.5 EGTA complete inhibition at 5 mM Leishmania infantum
3.6.1.5 additional information 0.1 mM N,N'-dicyclohexylcarbodiimide does not affect significantly ATP hydrolysis Leishmania infantum
3.6.1.5 Sodium azide 24% inhibition at 1 mM Leishmania infantum

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.6.1.5 Ca2+ ATP hydrolysis is more effective in the presence of 1 mM CaCl2 than in the presence of 1 mM MgCl2 Leishmania infantum
3.6.1.5 Mg2+ ATP hydrolysis is more effective in the presence of 1 mM CaCl2 than in the presence of 1 mM MgCl2 Leishmania infantum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.6.1.5 50000
-
 x * 50000, SDS-PAGE Leishmania infantum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.5 ATP + 2 H2O Leishmania infantum
-
 AMP + 2 phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.5 Leishmania infantum
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.1.5 promastigote
-
 Leishmania infantum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.5 ATP + 2 H2O
-
 Leishmania infantum AMP + 2 phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.6.1.5 ? x * 50000, SDS-PAGE Leishmania infantum

Synonyms

EC Number Synonyms Comment Organism
3.6.1.5 NTPDase 1
-
 Leishmania infantum
3.6.1.5 nucleoside triphosphate diphosphohydrolase 1
-
 Leishmania infantum