Literature summary extracted from

Kelly, S.L.; Lamb, D.C.; Corran, A.J.; Baldwin, B.C.; Parks, L.W.; Kelly, D.E.
Purification and reconstitution of activity of Saccharomyces cerevisiae P450 61, a sterol DELTA22-desaturase (1995), FEBS Lett., 377, 217-220.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.14.19.41	carbon monoxide	-	Saccharomyces cerevisiae

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
1.14.19.41	microsome	-	Saccharomyces cerevisiae	-	-

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.14.19.41	58000	-	x * 58000, SDS-PAGE	Saccharomyces cerevisiae

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.19.41	Saccharomyces cerevisiae	-	-	-
1.14.19.41	Saccharomyces cerevisiae DK2	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.14.19.41	aminooctyl-agarose column chromatography and hydroxylapatite column chromatography	Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.19.41	ergosta-5,7-dien-3beta-ol + NADPH + H+ + O2	-	Saccharomyces cerevisiae	ergosterol + NADP+ + H2O	-	?
1.14.19.41	ergosta-5,7-dien-3beta-ol + NADPH + H+ + O2	-	Saccharomyces cerevisiae DK2	ergosterol + NADP+ + H2O	-	?

Subunits

EC Number	Subunits	Comment	Organism
1.14.19.41	?	x * 58000, SDS-PAGE	Saccharomyces cerevisiae

Synonyms

EC Number	Synonyms	Comment	Organism
1.14.19.41	P450 61	-	Saccharomyces cerevisiae
1.14.19.41	sterol DELTA22-desaturase	-	Saccharomyces cerevisiae

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.14.19.41	NADPH	-	Saccharomyces cerevisiae

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)