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Literature summary extracted from

  • Antony, B.; Soffan, A.; Jakse, J.; Alfaifi, S.; Sutanto, K.; Aldosari, S.; Aldawood, A.; Pain, A.
    Genes involved in sex pheromone biosynthesis of Ephestia cautella, an important food storage pest, are determined by transcriptome sequencing (2015), BMC Genomics, 16, 532-557.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.19.32 transcriptome analysis, overview Cadra cautella

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.32 Cadra cautella
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.32 palmitoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ DELTA14 and DELTA9 desaturation to generate Z9,E12-14:acyl Cadra cautella (14E)-hexadec-14-enoyl-CoA + 2 ferricytochrome b5 + 2 H2O
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Synonyms

EC Number Synonyms Comment Organism
1.14.19.32 DELTA14-desaturase
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Cadra cautella

General Information

EC Number General Information Comment Organism
1.14.19.32 evolution origin and evolution of the DELTA14 desaturase, phylogenetic analysis and tree, detailed overview Cadra cautella
1.14.19.32 metabolism the enzyme is involved in the sex pheromone biosynthetic pathway. Two pathways exist, both initiate from C16:acyl-CoA, with one involving DELTA14 and DELTA9 desaturation to generate Z9,E12-14:acyl, and the other involving the chain shortening of C16:acyl-CoA to C14:acyl-CoA, followed by DELTA12 and DELTA9 desaturation to generate Z9,E12-14:acyl-CoA. Then, a final reduction and acetylation generates Z9,E12-14:OAc, overview. Desaturases introduce a double bond into the fatty acyl carbon chain, with strict regio- and stereo-selectivity Cadra cautella
1.14.19.32 physiological function the enzyme is involved in the synthesis of pheromone compound (Z,E)-9,12-tetradecadienyl acetate from pheromone precursor palmitoyl-CoA Cadra cautella