Literature summary extracted from
Pillai, J.K.; Venkadesh, S.; Ajees, A.A.; Rosen, B.P.; Bhattacharjee, H.
Mutations in the ArsA ATPase that restore interaction with the ArsD metallochaperone (2014), Biometals, 27, 1263-1275.
Activating Compound
EC Number |
Activating Compound |
Comment |
Organism |
Structure |
---|
7.3.2.7 |
ArsD |
a metallochaperone |
Escherichia coli |
|
Cloned(Commentary)
EC Number |
Cloned (Comment) |
Organism |
---|
7.3.2.7 |
expressed in Escherichia coli BL21(DE3) cells |
Escherichia coli |
Protein Variants
EC Number |
Protein Variants |
Comment |
Organism |
---|
7.3.2.7 |
D137V |
inactive |
Escherichia coli |
7.3.2.7 |
F120I |
inactive |
Escherichia coli |
7.3.2.7 |
Q56R |
the mutant exhibits significant metalloid-stimulated ATPase activity in vitro |
Escherichia coli |
Metals/Ions
EC Number |
Metals/Ions |
Comment |
Organism |
Structure |
---|
7.3.2.7 |
As3+ |
5.5-fold stimulation of ATPase activity at 0.1 mM |
Escherichia coli |
|
Natural Substrates/ Products (Substrates)
EC Number |
Natural Substrates |
Organism |
Comment (Nat. Sub.) |
Natural Products |
Comment (Nat. Pro.) |
Rev. |
Reac. |
---|
7.3.2.7 |
ATP + H2O + arsenite/in |
Escherichia coli |
- |
ADP + phosphate + arsenite/out |
- |
? |
|
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
7.3.2.7 |
Escherichia coli |
- |
- |
- |
Purification (Commentary)
EC Number |
Purification (Comment) |
Organism |
---|
7.3.2.7 |
- |
Escherichia coli |
Substrates and Products (Substrate)
EC Number |
Substrates |
Comment Substrates |
Organism |
Products |
Comment (Products) |
Rev. |
Reac. |
---|
7.3.2.7 |
ATP + H2O + arsenite/in |
- |
Escherichia coli |
ADP + phosphate + arsenite/out |
- |
? |
|
Synonyms
EC Number |
Synonyms |
Comment |
Organism |
---|
7.3.2.7 |
ArsA ATPase |
catalytic subunit of the ArsAB As(III) efflux pump |
Escherichia coli |