Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Beauchamp, E.; Tekpli, X.; Marteil, G.; Lagadic-Gossmann, D.; Legrand, P.; Rioux, V.
    N-myristoylation targets dihydroceramide DELTA4-desaturase 1 to mitochondria: Partial involvement in the apoptotic effect of myristic acid (2009), Biochimie, 91, 1411-1419.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.14.19.17 myristic acid
-
 Rattus norvegicus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.19.17 expressed in COS-7 cells Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.19.17 endoplasmic reticulum
-
 Rattus norvegicus 5783
-
1.14.19.17 mitochondrion N-myristoylation targets dihydroceramide DELTA4-desaturase 1 to mitochondria Rattus norvegicus 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.17 dihydroceramide + ferrocytochrome b5 + O2 + H+ Rattus norvegicus
-
 (4E)-sphing-4-enine ceramide + ferricytochrome b5 + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.17 Rattus norvegicus Q564G3
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.19.17 hepatocyte
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.17 dihydroceramide + ferrocytochrome b5 + O2 + H+
-
 Rattus norvegicus (4E)-sphing-4-enine ceramide + ferricytochrome b5 + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.17 DES1
-
 Rattus norvegicus
1.14.19.17 dihydroceramide DELTA4-desaturase 1
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.19.17 cytochrome b5
-
 Rattus norvegicus