EC Number | Application | Comment | Organism |
---|---|---|---|
3.4.22.15 | medicine | treatment with cathepsin L inhibitors significantly reduces the replication of caliciviruses | feline calicivirus |
3.4.22.15 | medicine | treatment with cathepsin L inhibitors significantly reduces the replication of caliciviruses | Murine norovirus 1 |
3.4.22.15 | medicine | treatment with cathepsin L inhibitors significantly reduces the replication of caliciviruses | Porcine enteric sapovirus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.22.15 | benzyloxycarbonyl-Phe-Tyr-CHO | - |
feline calicivirus | |
3.4.22.15 | benzyloxycarbonyl-Phe-Tyr-CHO | - |
Murine norovirus 1 | |
3.4.22.15 | benzyloxycarbonyl-Phe-Tyr-CHO | - |
Porcine enteric sapovirus | |
3.4.22.15 | MDL28170 | - |
feline calicivirus | |
3.4.22.15 | MDL28170 | - |
Murine norovirus 1 | |
3.4.22.15 | MDL28170 | - |
Porcine enteric sapovirus | |
3.4.22.15 | additional information | not inhibited by CA074Me | feline calicivirus | |
3.4.22.15 | additional information | not inhibited by CA074Me | Murine norovirus 1 | |
3.4.22.15 | additional information | not inhibited by CA074Me | Porcine enteric sapovirus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.22.15 | feline calicivirus | - |
- |
- |
3.4.22.15 | Murine norovirus 1 | - |
- |
- |
3.4.22.15 | Porcine enteric sapovirus | - |
- |
- |
EC Number | General Information | Comment | Organism |
---|---|---|---|
3.4.22.15 | physiological function | cathepsin L activity is required for calicivirus replication | feline calicivirus |
3.4.22.15 | physiological function | cathepsin L activity is required for calicivirus replication | Murine norovirus 1 |
3.4.22.15 | physiological function | cathepsin L activity is required for calicivirus replication | Porcine enteric sapovirus |