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Literature summary extracted from

  • Uehara, L.A.; Moreira, O.C.; Oliveira, A.C.; Azambuja, P.; Lima, A.P.; Britto, C.; dos Santos, A.L.; Branquinha, M.H.; dAvila-Levy, C.M.
    Cruzipain promotes Trypanosoma cruzi adhesion to Rhodnius prolixus midgut (2012), PLoS Negl. Trop. Dis., 6, e1958.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.51 antipain
-
 Trypanosoma cruzi
3.4.22.51 chagasin
-
 Trypanosoma cruzi
3.4.22.51 cystatin
-
 Trypanosoma cruzi
3.4.22.51 E-64
-
 Trypanosoma cruzi
3.4.22.51 iodoacetamide
-
 Trypanosoma cruzi
3.4.22.51 leupeptin
-
 Trypanosoma cruzi
3.4.22.51 additional information not inhibited by CA-074-OMe Trypanosoma cruzi

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.22.51 lysosome
-
 Trypanosoma cruzi 5764
-

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.51 Trypanosoma cruzi
-
-
-
3.4.22.51 Trypanosoma cruzi Dm28c
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.51 epimastigote
-
 Trypanosoma cruzi
-

Expression

EC Number Organism Comment Expression
3.4.22.51 Trypanosoma cruzi the levels of cruzipain expression by wild-type parasites are enhanced after in vivo passage in Rhodnius prolixus up

General Information

EC Number General Information Comment Organism
3.4.22.51 physiological function cruzipain promotes Trypanosoma cruzi adhesion to Rhodnius prolixus midgut Trypanosoma cruzi