EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.22.46 | (2S,3R,4R)-2-{[2-(2,3-dihydroxyphenyl)-5,8-dihydroxy-4-oxo-4H-chromen-7-yl]oxy}-4-hydroxy-4-(hydroxymethyl)tetrahydrofuran-3-yl alpha-D-galactopyranoside | - |
Mycobacterium tuberculosis | |
3.4.22.46 | 2-(3,4-dihydroxyphenyl)ethyl 4-O-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-6-O-alpha-L-lyxopyranosyl-beta-D-glucopyranoside | - |
Mycobacterium tuberculosis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.22.46 | Mycobacterium tuberculosis | P9WKA1 | - |
- |
3.4.22.46 | Mycobacterium tuberculosis H37Rv | P9WKA1 | - |
- |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.22.46 | leader peptidase B | - |
Mycobacterium tuberculosis |
3.4.22.46 | LepB | - |
Mycobacterium tuberculosis |
EC Number | General Information | Comment | Organism |
---|---|---|---|
3.4.22.46 | malfunction | the inhibition of LepB results in repressing the cleavage of the signal peptide from the preproteins which would lead to arresting the folding of proteins which are essential for the growth and pathogenesis of Mycobacterium tuberculosis into their active mature conformation | Mycobacterium tuberculosis |