EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.7 | HI-6 | reactivates the sarin- and paraoxon-inhibited enzyme | Cavia porcellus | |
3.1.1.7 | HI-6 | reactivates the sarin- and paraoxon-inhibited enzyme | Homo sapiens | |
3.1.1.7 | HI-6 | reactivates the sarin- and paraoxon-inhibited enzyme | Sus scrofa | |
3.1.1.7 | obidoxime | reactivates the sarin- and paraoxon-inhibited enzyme | Cavia porcellus | |
3.1.1.7 | obidoxime | reactivates the sarin- and paraoxon-inhibited enzyme | Homo sapiens | |
3.1.1.7 | obidoxime | reactivates the sarin- and paraoxon-inhibited enzyme | Sus scrofa |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.7 | paraoxon | more than 95% inhibition at 0.001 mM | Cavia porcellus | |
3.1.1.7 | paraoxon | more than 95% inhibition at 0.001 mM | Homo sapiens | |
3.1.1.7 | paraoxon | more than 95% inhibition at 0.001 mM | Sus scrofa | |
3.1.1.7 | sarin | more than 95% inhibition at 50 nM | Cavia porcellus | |
3.1.1.7 | sarin | more than 95% inhibition at 30 nM | Homo sapiens | |
3.1.1.7 | sarin | more than 95% inhibition at 50 nM | Sus scrofa |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.1.7 | 0.0923 | - |
acetylthiocholine | enzyme from erythrocyte, pH and temperature not specified in the publication | Homo sapiens | |
3.1.1.7 | 0.0924 | - |
acetylthiocholine | enzyme from muscle, pH and temperature not specified in the publication | Homo sapiens | |
3.1.1.7 | 0.1011 | - |
acetylthiocholine | enzyme from brain, pH and temperature not specified in the publication | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.7 | acetylcholine + H2O | Cavia porcellus | - |
choline + acetate | - |
? | |
3.1.1.7 | acetylcholine + H2O | Homo sapiens | - |
choline + acetate | - |
? | |
3.1.1.7 | acetylcholine + H2O | Sus scrofa | - |
choline + acetate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.1.7 | Cavia porcellus | - |
- |
- |
3.1.1.7 | Homo sapiens | - |
- |
- |
3.1.1.7 | Sus scrofa | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.1.7 | brain | - |
Cavia porcellus | - |
3.1.1.7 | brain | - |
Homo sapiens | - |
3.1.1.7 | brain | - |
Sus scrofa | - |
3.1.1.7 | erythrocyte | - |
Cavia porcellus | - |
3.1.1.7 | erythrocyte | - |
Homo sapiens | - |
3.1.1.7 | erythrocyte | - |
Sus scrofa | - |
3.1.1.7 | muscle | - |
Cavia porcellus | - |
3.1.1.7 | muscle | - |
Homo sapiens | - |
3.1.1.7 | muscle | - |
Sus scrofa | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.7 | acetylcholine + H2O | - |
Cavia porcellus | choline + acetate | - |
? | |
3.1.1.7 | acetylcholine + H2O | - |
Homo sapiens | choline + acetate | - |
? | |
3.1.1.7 | acetylcholine + H2O | - |
Sus scrofa | choline + acetate | - |
? | |
3.1.1.7 | acetylthiocholine + H2O | - |
Cavia porcellus | thiocholine + acetate | - |
? | |
3.1.1.7 | acetylthiocholine + H2O | - |
Homo sapiens | thiocholine + acetate | - |
? | |
3.1.1.7 | acetylthiocholine + H2O | - |
Sus scrofa | thiocholine + acetate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.1.7 | AChE | - |
Cavia porcellus |
3.1.1.7 | AChE | - |
Homo sapiens |
3.1.1.7 | AChE | - |
Sus scrofa |