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Literature summary extracted from

  • Worek, F.; Aurbek, N.; Wille, T.; Eyer, P.; Thiermann, H.
    Kinetic analysis of interactions of paraoxon and oximes with human, Rhesus monkey, swine, rabbit, rat and guinea pig acetylcholinesterase (2011), Toxicol. Lett., 200, 19-23.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.7 HI-6
-
 Cavia porcellus
3.1.1.7 HI-6
-
 Homo sapiens
3.1.1.7 HI-6
-
 Oryctolagus cuniculus
3.1.1.7 HI-6
-
 Rattus norvegicus
3.1.1.7 HI-6
-
 Sus scrofa
3.1.1.7 MMB-4
-
 Cavia porcellus
3.1.1.7 MMB-4
-
 Homo sapiens
3.1.1.7 MMB-4
-
 Oryctolagus cuniculus
3.1.1.7 MMB-4
-
 Rattus norvegicus
3.1.1.7 MMB-4
-
 Sus scrofa
3.1.1.7 obidoxime
-
 Cavia porcellus
3.1.1.7 obidoxime
-
 Homo sapiens
3.1.1.7 obidoxime
-
 Oryctolagus cuniculus
3.1.1.7 obidoxime
-
 Rattus norvegicus
3.1.1.7 obidoxime
-
 Sus scrofa
3.1.1.7 paraoxon
-
 Cavia porcellus
3.1.1.7 paraoxon
-
 Homo sapiens
3.1.1.7 paraoxon
-
 Oryctolagus cuniculus
3.1.1.7 paraoxon
-
 Rattus norvegicus
3.1.1.7 paraoxon
-
 Sus scrofa
3.1.1.7 pralidoxime
-
 Cavia porcellus
3.1.1.7 pralidoxime
-
 Homo sapiens
3.1.1.7 pralidoxime
-
 Oryctolagus cuniculus
3.1.1.7 pralidoxime
-
 Rattus norvegicus
3.1.1.7 pralidoxime
-
 Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.7 acetylcholine + H2O Cavia porcellus
-
 choline + acetate
-
 ?
3.1.1.7 acetylcholine + H2O Homo sapiens
-
 choline + acetate
-
 ?
3.1.1.7 acetylcholine + H2O Rattus norvegicus
-
 choline + acetate
-
 ?
3.1.1.7 acetylcholine + H2O Sus scrofa
-
 choline + acetate
-
 ?
3.1.1.7 acetylcholine + H2O Oryctolagus cuniculus
-
 choline + acetate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.7 Cavia porcellus
-
-
-
3.1.1.7 Homo sapiens
-
-
-
3.1.1.7 Oryctolagus cuniculus
-
-
-
3.1.1.7 Rattus norvegicus
-
-
-
3.1.1.7 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.7 erythrocyte
-
 Cavia porcellus
-
3.1.1.7 erythrocyte
-
 Homo sapiens
-
3.1.1.7 erythrocyte
-
 Rattus norvegicus
-
3.1.1.7 erythrocyte
-
 Sus scrofa
-
3.1.1.7 erythrocyte
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.7 acetylcholine + H2O
-
 Cavia porcellus choline + acetate
-
 ?
3.1.1.7 acetylcholine + H2O
-
 Homo sapiens choline + acetate
-
 ?
3.1.1.7 acetylcholine + H2O
-
 Rattus norvegicus choline + acetate
-
 ?
3.1.1.7 acetylcholine + H2O
-
 Sus scrofa choline + acetate
-
 ?
3.1.1.7 acetylcholine + H2O
-
 Oryctolagus cuniculus choline + acetate
-
 ?
3.1.1.7 acetylthiocholine + H2O
-
 Cavia porcellus thiocholine + acetate
-
 ?
3.1.1.7 acetylthiocholine + H2O
-
 Homo sapiens thiocholine + acetate
-
 ?
3.1.1.7 acetylthiocholine + H2O
-
 Rattus norvegicus thiocholine + acetate
-
 ?
3.1.1.7 acetylthiocholine + H2O
-
 Sus scrofa thiocholine + acetate
-
 ?
3.1.1.7 acetylthiocholine + H2O
-
 Oryctolagus cuniculus thiocholine + acetate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.7 AChE
-
 Cavia porcellus
3.1.1.7 AChE
-
 Homo sapiens
3.1.1.7 AChE
-
 Rattus norvegicus
3.1.1.7 AChE
-
 Sus scrofa
3.1.1.7 AChE
-
 Oryctolagus cuniculus