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Literature summary extracted from

  • Tocchini-Valentini, G.D.; Tocchini-Valentini, G.P.
    Avatar pre-tRNAs help elucidate the properties of tRNA-splicing endonucleases that produce tRNA from permuted genes (2012), Proc. Natl. Acad. Sci. USA, 109, 21325-21329.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.6.1.16 pretRNA Schizosaccharomyces pombe
-
 a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
 ?
4.6.1.16 pretRNA Methanocaldococcus jannaschii
-
 a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.16 Methanocaldococcus jannaschii Q58819
-
-
4.6.1.16 Schizosaccharomyces pombe
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.16 pretRNA
-
 Schizosaccharomyces pombe a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
 ?
4.6.1.16 pretRNA
-
 Methanocaldococcus jannaschii a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
 ?

Subunits

EC Number Subunits Comment Organism
4.6.1.16 heterotetramer
-
 Schizosaccharomyces pombe
4.6.1.16 homotetramer
-
 Methanocaldococcus jannaschii

Synonyms

EC Number Synonyms Comment Organism
4.6.1.16 MJ1424 locus name Methanocaldococcus jannaschii
4.6.1.16 tRNA endonuclease
-
 Schizosaccharomyces pombe
4.6.1.16 tRNA endonuclease
-
 Methanocaldococcus jannaschii
4.6.1.16 tRNA-splicing endonuclease
-
 Schizosaccharomyces pombe
4.6.1.16 tRNA-splicing endonuclease
-
 Methanocaldococcus jannaschii