Literature summary extracted from

Bardowell, S.A.; Duan, F.; Manor, D.; Swanson, J.E.; Parker, R.S.
Disruption of mouse cytochrome P450 4F14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism (2012), J. Biol. Chem., 287, 26077-26086.

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.14.14.78	58000	-	x * 58000, SDS-PAGE	Mus musculus

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.14.14.78	phylloquinone + [reduced NADPH-hemoprotein reductase] + O2	Mus musculus	-	omega-hydroxyphylloquinone + [oxidized NADPH-hemoprotein reductase] + H2O	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.14.78	Mus musculus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.14.14.78	liver	-	Mus musculus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.14.78	phylloquinone + [reduced NADPH-hemoprotein reductase] + O2	-	Mus musculus	omega-hydroxyphylloquinone + [oxidized NADPH-hemoprotein reductase] + H2O	-	?

Subunits

EC Number	Subunits	Comment	Organism
1.14.14.78	?	x * 58000, SDS-PAGE	Mus musculus

Synonyms

EC Number	Synonyms	Comment	Organism
1.14.14.78	CYP4F14	-	Mus musculus

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.14.14.78	NADPH	-	Mus musculus

General Information

EC Number	General Information	Comment	Organism
1.14.14.78	malfunction	disruption of the CYP4F14 gene causes severe perturbations in vitamin E metabolism	Mus musculus
1.14.14.78	metabolism	CYP4F14 is the major but not the only vitamin E-omega-hydroxylase in mice	Mus musculus

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Release 2023.1 (January 2023)