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Literature summary extracted from

  • Wu, Y.; Wang, Q.; Hillwig, M.; Peters, R.
    Picking sides: Distinct roles for CYP76M6 and CYP76M8 in rice oryzalexin biosynthesis (2013), Biochem. J., 454, 209-216.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.14.70 expressed in Escherichia coli C41 cells Oryza sativa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.70 ent-sandaracopimaradiene + NADPH + H+ + O2 Oryza sativa
-
 ent-sandaracopimaradien-3beta-ol + NADP+ + H2O
-
 ?
1.14.14.122 ent-sandaracopimaradien-3beta-ol + [reduced NADPH-hemoprotein reductase] + O2 Oryza sativa
-
 oryzalexin E + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.123 ent-sandaracopimaradien-3beta-ol + [reduced NADPH-hemoprotein reductase] + O2 Oryza sativa
-
 oryzalexin D + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.70 Oryza sativa
-
-
-
1.14.14.122 Oryza sativa
-
-
-
1.14.14.123 Oryza sativa
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.70 7beta-hydroxy-ent-sandaracopimaradiene + [reduced NADPH-hemoprotein reductase] + O2 poor reaction Oryza sativa oryzalexin D + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.70 ent-sandaracopimaradiene + NADPH + H+ + O2
-
 Oryza sativa ent-sandaracopimaradien-3beta-ol + NADP+ + H2O
-
 ?
1.14.14.122 ent-sandaracopimaradien-3beta-ol + [reduced NADPH-hemoprotein reductase] + O2
-
 Oryza sativa oryzalexin E + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.123 ent-sandaracopimaradien-3beta-ol + [reduced NADPH-hemoprotein reductase] + O2
-
 Oryza sativa oryzalexin D + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.70 CYP701A8
-
 Oryza sativa
1.14.14.122 CYP76M6
-
 Oryza sativa
1.14.14.123 CYP76M8
-
 Oryza sativa

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.14.70 NADPH
-
 Oryza sativa