EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.14.78 | additional information | unaffected by lauric acid, palmitic acid, and prostaglandin F2alpha | Homo sapiens | |
1.14.14.78 | prostaglandin A1 | - |
Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.14.14.78 | microsome | - |
Homo sapiens | - |
- |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.14.78 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.14.14.78 | tryptamine CH-Sepharose column chromatography, DE-53 cellulose column chromatography, and Hypatite C column chromatography | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.14.78 | liver | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.14.78 | arachidonic acid + [reduced NADPH-hemoprotein reductase] + O2 | - |
Homo sapiens | 20-hydroxyarachidonic acid + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
1.14.14.78 | leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2 | - |
Homo sapiens | 20-hydroxyleukotriene B4 + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.14.78 | CYP4F2 | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.14.78 | NADPH | - |
Homo sapiens |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.14.14.78 | physiological function | CYP4F2 is the principle leukotriene B4 omega-hydroxylating enzyme expressed in human liver and plays an important role in regulating circulating as well as hepatic levels of this powerful proinflammatory eicosanoid | Homo sapiens |