EC Number | Cloned (Comment) | Organism |
---|---|---|
3.5.1.1 | - |
Pyrococcus furiosus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.5.1.1 | Pyrococcus furiosus | Q8TZE8 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.5.1.1 | - |
Pyrococcus furiosus |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.5.1.1 | dimer | the linker of the two-domain dimeric enzyme is found to be dispensable. Domains of this enzyme assemble without the linker into a conjoined tetrameric form that exhibits higher activity than the parent enzyme.The global shape and quaternary structure of the conjoined enzyme are also similar to the wild-type enzyme, as observed by their solution scattering profiles and X-ray crystallographic data. Comparison of the crystal structures of substrate-bound and unbound enzymes reveal an altogether new active-site composition and mechanism of action | Pyrococcus furiosus |