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Literature summary extracted from

  • Amengual, J.; Gouranton, E.; van Helden, Y.G.; Hessel, S.; Ribot, J.; Kramer, E.; Kiec-Wilk, B.; Razny, U.; Lietz, G.; Wyss, A.; Dembinska-Kiec, A.; Palou, A.; Keijer, J.; Landrier, J.F.; Bonet, M.L.; von Lintig, J.
    Beta-carotene reduces body adiposity of mice via BCMO1 (2011), PLoS ONE, 6, e20644.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.13.11.63 beta-carotene + O2 Mus musculus
-
2 all-trans-retinal
-
?
1.13.11.63 additional information Mus musculus 25-hydroxycholesterol is a secondary autoxidation product derived from 3beta-hydroxy-cholest-5-ene-25-hydroperoxide, a hydroperoxide identified in air-aged cholesterol ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.63 Mus musculus Q9JJS6 gene Bcmo1
-
1.13.11.71 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.63 adipocyte
-
Mus musculus
-
1.13.11.63 white adipose tissue
-
Mus musculus
-
1.13.11.71 adipose tissue
-
Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.63 beta-carotene + O2
-
Mus musculus 2 all-trans-retinal
-
?
1.13.11.63 additional information 25-hydroxycholesterol is a secondary autoxidation product derived from 3beta-hydroxy-cholest-5-ene-25-hydroperoxide, a hydroperoxide identified in air-aged cholesterol Mus musculus ?
-
?

Synonyms

EC Number Synonyms Comment Organism
1.13.11.63 BC-15,15'-oxygenase
-
Mus musculus
1.13.11.63 Bcmo1
-
Mus musculus
1.13.11.71 BC-9',10'-oxygenase
-
Mus musculus
1.13.11.71 Bcdo2
-
Mus musculus

Expression

EC Number Organism Comment Expression
1.13.11.71 Mus musculus a marked up-regulation of Bcdo2 expression in inguinal white adipose tissue of Bcmo1-null mice is shown, both with control and beta-carotene diet up