EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.13.11.34 | (10E,12E)-octadeca-10,12-dien-8-ynoic acid | - |
Rattus norvegicus | |
1.13.11.34 | (11E)-octadec-11-en-9-ynoic acid | - |
Rattus norvegicus | |
1.13.11.34 | (1E)-1-((1-[(1Z)-prop-1-en-1-yldisulfanyl]propyl)sulfinyl)prop-1-ene | - |
Rattus norvegicus | |
1.13.11.34 | (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | - |
Rattus norvegicus | |
1.13.11.34 | ([3-chloro-5-(2,3-dihydro-1H-inden-4-ylamino)phenyl]sulfanyl)acetic acid | - |
Rattus norvegicus | |
1.13.11.34 | 1,4a-dimethyl-7-(propan-2-yl)-1-(prop-1-en-2-yl)-1,2,3,4,4a,4b,5,6,10,10a-decahydrophenanthrene (non-preferred name) | - |
Rattus norvegicus | |
1.13.11.34 | 1-(3,4-difluorophenyl)-1,2,4-triazinan-3-one | - |
Rattus norvegicus | |
1.13.11.34 | 1-(3-bromophenyl)-1,2,4-triazinan-3-one | - |
Rattus norvegicus | |
1.13.11.34 | 1-(3-chlorophenyl)-1,2,4-triazinan-3-one | - |
Rattus norvegicus | |
1.13.11.34 | 1-(3-ethylphenyl)-1,2,4-triazinan-3-one | - |
Rattus norvegicus | |
1.13.11.34 | 1-(3-hydroxyphenyl)-3-[4-(methylsulfonyl)phenyl]prop-2-yn-1-one | - |
Rattus norvegicus | |
1.13.11.34 | 1-(6-methylpyridin-2-yl)-1,2,4-triazinan-3-one | - |
Rattus norvegicus | |
1.13.11.34 | 1-hydroxy-1-[1-(5-methoxy-1-methyl-1H-indol-2-yl)ethyl]urea | - |
Rattus norvegicus | |
1.13.11.34 | 1-phenyl-5-(propan-2-yl)-1,2,4-triazinan-3-one | - |
Rattus norvegicus | |
1.13.11.34 | 1-[1-(6-tert-butyl-1-benzothiophen-2-yl)ethyl]-1-hydroxyurea | - |
Rattus norvegicus | |
1.13.11.34 | 1-[3-(benzyloxy)phenyl]-1,2,4-triazinan-3-one | - |
Rattus norvegicus | |
1.13.11.34 | 1-[4-([3-fluoro-5-[4-(methylsulfinyl)tetrahydro-2H-pyran-4-yl]phenoxy]methyl)phenyl]-2-methyl-1H-imidazole | - |
Rattus norvegicus | |
1.13.11.34 | 1-[4-([3-fluoro-5-[4-(methylsulfonyl)tetrahydro-2H-pyran-4-yl]phenoxy]methyl)phenyl]-2-methyl-1H-imidazole | - |
Rattus norvegicus | |
1.13.11.34 | 2-(2,4-dihydroxyphenyl)-8,8-dimethyl-3-(3-methylbut-2-en-1-yl)-4H,8H-pyrano[2,3-f]chromen-4-one | - |
Rattus norvegicus | |
1.13.11.34 | 2-(2-[ethyl(hydroxy)amino]ethyl)dibenzo[b,e]oxepin-11(6H)-one | - |
Rattus norvegicus | |
1.13.11.34 | 2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol | - |
Rattus norvegicus | |
1.13.11.34 | 2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol | - |
Rattus norvegicus | |
1.13.11.34 | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one | - |
Rattus norvegicus | |
1.13.11.34 | 2-(3-methylbut-2-en-1-yl)-6H-[1]benzofuro[3,2-c]chromene-3,6,9-triol | - |
Rattus norvegicus | |
1.13.11.34 | 2-(3-[hydroxy(methyl)amino]propyl)dibenzo[b,e]oxepin-11(6H)-one | - |
Rattus norvegicus | |
1.13.11.34 | 3-(2-(2-[(4-chlorophenyl)sulfanyl]ethoxy)-3-methoxy-5-[5-(3,4,5-trimethoxyphenyl)tetrahydrofuran-2-yl]benzyl)-1-hydroxy-1-methylurea | - |
Rattus norvegicus | |
1.13.11.34 | 3-(4,5-dihydroxy-2-methyl-9,10-dioxo-4a,9,9a,10-tetrahydroanthracen-1-yl)-2-hydroxy-4,6-dimethoxybenzoic acid | - |
Rattus norvegicus | |
1.13.11.34 | 3-ethoxy-11-oxours-12-en-23-oic acid | - |
Rattus norvegicus | |
1.13.11.34 | 3-[4-(methylsulfonyl)phenyl]-1-[4-(propan-2-yl)phenyl]prop-2-yn-1-one | - |
Rattus norvegicus | |
1.13.11.34 | 3-[5-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxyphenyl]-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one | - |
Rattus norvegicus | |
1.13.11.34 | 4,9-dimethoxy-3-methyl-9,10-dihydrophenanthrene-2,7-diol | - |
Rattus norvegicus | |
1.13.11.34 | 4-(3-fluoro-5-[[4-(2-methyl-1H-imidazol-1-yl)benzyl]oxy]phenyl)-N-methyltetrahydro-2H-pyran-4-carboxamide | - |
Rattus norvegicus | |
1.13.11.34 | 4-(3-fluoro-5-[[4-(2-methyl-1H-imidazol-1-yl)benzyl]oxy]phenyl)tetrahydro-2H-pyran-4-ol | - |
Rattus norvegicus | |
1.13.11.34 | 4-(3-fluoro-5[[4-(2-methyl-1H-imidazol-1-yl)benzyl]oxy]phenyl)tetrahydro-2H-pyran-4-carboxylic acid | - |
Rattus norvegicus | |
1.13.11.34 | 4-(6-methoxynaphthalen-2-yl)butan-2-one | - |
Rattus norvegicus | |
1.13.11.34 | 4-(acetyloxy)-2-[4-(acetyloxy)-6-methylhept-5-en-2-yl]cyclohexyl (2Z)-2-methylbut-2-enoate | - |
Rattus norvegicus | |
1.13.11.34 | 4-(furan-3-yl)-7-[[2-(tetrahydro-2H-pyran-4-yl)pyridin-4-yl]methoxy]naphthalene-2-carbonitrile | - |
Rattus norvegicus | |
1.13.11.34 | 4-(furan-3-yl)-7-[[7-(tetrahydro-2H-pyran-4-yl)-1,2,3,4-tetrahydroquinolin-2-yl]oxy]naphthalene-2-carbonitrile | - |
Rattus norvegicus | |
1.13.11.34 | 5,5'-di(prop-2-en-1-yl)biphenyl-2,2'-diol | - |
Rattus norvegicus | |
1.13.11.34 | 5,5-dimethyl-1-phenyl-1,2,4-triazinan-3-one | - |
Rattus norvegicus | |
1.13.11.34 | 5-(4-fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole | - |
Rattus norvegicus | |
1.13.11.34 | 5-butyl-1-phenyl-1,2,4-triazinan-3-one | - |
Rattus norvegicus | |
1.13.11.34 | 5-ethyl-1-phenyl-1,2,4-triazinan-3-one | - |
Rattus norvegicus | |
1.13.11.34 | 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol | - |
Rattus norvegicus | |
1.13.11.34 | 7,8-dihydroxy-2H-chromen-2-one | - |
Rattus norvegicus | |
1.13.11.34 | N-hydroxy-N-[(2E)-3-(3-phenoxyphenyl)prop-2-en-1-yl]acetamide | - |
Rattus norvegicus | |
1.13.11.34 | N-hydroxy-N-[1-(1-methyl-1H-indol-2-yl)ethyl]acetamide | - |
Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.13.11.34 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.13.11.34 | leukemia cell | - |
Rattus norvegicus | - |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.13.11.34 | 5-LOX | - |
Rattus norvegicus |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
1.13.11.34 | 0.000195 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 1-[4-([3-fluoro-5-[4-(methylsulfonyl)tetrahydro-2H-pyran-4-yl]phenoxy]methyl)phenyl]-2-methyl-1H-imidazole | |
1.13.11.34 | 0.00034 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 1-[4-([3-fluoro-5-[4-(methylsulfinyl)tetrahydro-2H-pyran-4-yl]phenoxy]methyl)phenyl]-2-methyl-1H-imidazole | |
1.13.11.34 | 0.0005 | - |
pH and temperature not specified in the publication | Rattus norvegicus | (1E)-1-((1-[(1Z)-prop-1-en-1-yldisulfanyl]propyl)sulfinyl)prop-1-ene | |
1.13.11.34 | 0.0005 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 3-[5-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxyphenyl]-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one | |
1.13.11.34 | 0.00054 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 4-(3-fluoro-5[[4-(2-methyl-1H-imidazol-1-yl)benzyl]oxy]phenyl)tetrahydro-2H-pyran-4-carboxylic acid | |
1.13.11.34 | 0.0006 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 4-(3-fluoro-5-[[4-(2-methyl-1H-imidazol-1-yl)benzyl]oxy]phenyl)tetrahydro-2H-pyran-4-ol | |
1.13.11.34 | 0.00119 | - |
pH and temperature not specified in the publication | Rattus norvegicus | N-hydroxy-N-[1-(1-methyl-1H-indol-2-yl)ethyl]acetamide | |
1.13.11.34 | 0.00137 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol | |
1.13.11.34 | 0.0015 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 3-ethoxy-11-oxours-12-en-23-oic acid | |
1.13.11.34 | 0.002 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 5,5'-di(prop-2-en-1-yl)biphenyl-2,2'-diol | |
1.13.11.34 | 0.0021 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 1-(3-bromophenyl)-1,2,4-triazinan-3-one | |
1.13.11.34 | 0.0028 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 1-(3,4-difluorophenyl)-1,2,4-triazinan-3-one | |
1.13.11.34 | 0.003 | - |
pH and temperature not specified in the publication | Rattus norvegicus | (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | |
1.13.11.34 | 0.003 | - |
value above, pH and temperature not specified in the publication | Rattus norvegicus | 4-(6-methoxynaphthalen-2-yl)butan-2-one | |
1.13.11.34 | 0.003 | - |
value above, pH and temperature not specified in the publication | Rattus norvegicus | 5-(4-fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole | |
1.13.11.34 | 0.0032 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one | |
1.13.11.34 | 0.0035 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 1-(3-chlorophenyl)-1,2,4-triazinan-3-one | |
1.13.11.34 | 0.0036 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 2-(3-methylbut-2-en-1-yl)-6H-[1]benzofuro[3,2-c]chromene-3,6,9-triol | |
1.13.11.34 | 0.0038 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 1-hydroxy-1-[1-(5-methoxy-1-methyl-1H-indol-2-yl)ethyl]urea | |
1.13.11.34 | 0.0038 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 4-(furan-3-yl)-7-[[7-(tetrahydro-2H-pyran-4-yl)-1,2,3,4-tetrahydroquinolin-2-yl]oxy]naphthalene-2-carbonitrile | |
1.13.11.34 | 0.0039 | - |
pH and temperature not specified in the publication | Rattus norvegicus | ([3-chloro-5-(2,3-dihydro-1H-inden-4-ylamino)phenyl]sulfanyl)acetic acid | |
1.13.11.34 | 0.0039 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 1-(6-methylpyridin-2-yl)-1,2,4-triazinan-3-one | |
1.13.11.34 | 0.0039 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 1-phenyl-5-(propan-2-yl)-1,2,4-triazinan-3-one | |
1.13.11.34 | 0.0042 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 3-(4,5-dihydroxy-2-methyl-9,10-dioxo-4a,9,9a,10-tetrahydroanthracen-1-yl)-2-hydroxy-4,6-dimethoxybenzoic acid | |
1.13.11.34 | 0.0048 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 5,5-dimethyl-1-phenyl-1,2,4-triazinan-3-one | |
1.13.11.34 | 0.0049 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 1-[3-(benzyloxy)phenyl]-1,2,4-triazinan-3-one | |
1.13.11.34 | 0.0049 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 2-(3-[hydroxy(methyl)amino]propyl)dibenzo[b,e]oxepin-11(6H)-one | |
1.13.11.34 | 0.005 | - |
pH and temperature not specified in the publication | Rattus norvegicus | (10E,12E)-octadeca-10,12-dien-8-ynoic acid | |
1.13.11.34 | 0.0055 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 2-(2-[ethyl(hydroxy)amino]ethyl)dibenzo[b,e]oxepin-11(6H)-one | |
1.13.11.34 | 0.0055 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 4-(furan-3-yl)-7-[[2-(tetrahydro-2H-pyran-4-yl)pyridin-4-yl]methoxy]naphthalene-2-carbonitrile | |
1.13.11.34 | 0.0056 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 1-[1-(6-tert-butyl-1-benzothiophen-2-yl)ethyl]-1-hydroxyurea | |
1.13.11.34 | 0.006 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 5-ethyl-1-phenyl-1,2,4-triazinan-3-one | |
1.13.11.34 | 0.0066 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 1-(3-ethylphenyl)-1,2,4-triazinan-3-one | |
1.13.11.34 | 0.0068 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 4-(3-fluoro-5-[[4-(2-methyl-1H-imidazol-1-yl)benzyl]oxy]phenyl)-N-methyltetrahydro-2H-pyran-4-carboxamide | |
1.13.11.34 | 0.0069 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 7,8-dihydroxy-2H-chromen-2-one | |
1.13.11.34 | 0.0077 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 4-(acetyloxy)-2-[4-(acetyloxy)-6-methylhept-5-en-2-yl]cyclohexyl (2Z)-2-methylbut-2-enoate | |
1.13.11.34 | 0.0084 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 5-butyl-1-phenyl-1,2,4-triazinan-3-one | |
1.13.11.34 | 0.0085 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 4,9-dimethoxy-3-methyl-9,10-dihydrophenanthrene-2,7-diol | |
1.13.11.34 | 0.01 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 3-(2-(2-[(4-chlorophenyl)sulfanyl]ethoxy)-3-methoxy-5-[5-(3,4,5-trimethoxyphenyl)tetrahydrofuran-2-yl]benzyl)-1-hydroxy-1-methylurea | |
1.13.11.34 | 0.02 | 2 | pH and temperature not specified in the publication | Rattus norvegicus | 2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol | |
1.13.11.34 | 0.029 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 1,4a-dimethyl-7-(propan-2-yl)-1-(prop-1-en-2-yl)-1,2,3,4,4a,4b,5,6,10,10a-decahydrophenanthrene (non-preferred name) | |
1.13.11.34 | 0.03 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol | |
1.13.11.34 | 0.06 | - |
pH and temperature not specified in the publication | Rattus norvegicus | (11E)-octadec-11-en-9-ynoic acid | |
1.13.11.34 | 0.1 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 2-(2,4-dihydroxyphenyl)-8,8-dimethyl-3-(3-methylbut-2-en-1-yl)-4H,8H-pyrano[2,3-f]chromen-4-one | |
1.13.11.34 | 0.15 | - |
pH and temperature not specified in the publication | Rattus norvegicus | N-hydroxy-N-[(2E)-3-(3-phenoxyphenyl)prop-2-en-1-yl]acetamide | |
1.13.11.34 | 0.3 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 1-(3-hydroxyphenyl)-3-[4-(methylsulfonyl)phenyl]prop-2-yn-1-one | |
1.13.11.34 | 0.32 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 3-[4-(methylsulfonyl)phenyl]-1-[4-(propan-2-yl)phenyl]prop-2-yn-1-one |